A 3D-printed device for separating short-lived radioisotopes from target ions.

IF 1.8 3区工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR

Applied Radiation and Isotopes Pub Date : 2025-07-16 DOI:10.1016/j.apradiso.2025.112052

Go Kagawa, Yumi Sugo, Tomotaka Tachibana, Ouju Nogawa, Kentaro Saeki, Noriko S Ishioka, Masanobu Mori, Kei Toda, Shin-Ichi Ohira

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引用次数: 0

Abstract

The separation of metal radioactive isotopes (RIs) generated in a cyclotron is a crucial process. This report describes the development of a newly designed 3D-printed device for such separation. The 3D-printing fabrication approach offers a cost-effective method for manufacturing single-use devices. The overall separation process involved selective chelate formation, adsorption of the target ion, and finally, UV radiation-induced decomposition of the metal complex. All of these steps are achieved in-line in the developed device. Moreover, this novel system can handle practical solution volumes (approximately 10 mL) containing the dissolved RI and target and is designed to be disposable. The separation performance was evaluated using the following RI/target systems: ⁶⁷Ga/Zn and ⁸⁹Zr/Y. The developed device enables universal separation by changing the chelate formation conditions, i.e., acid concentration. Nearly quantitative RI recoveries are achieved without target contamination, and a highly pure RI solution can be obtained automatically within 30 min. The universal and cost-effective separation device presented herein is therefore suitable for a wide range of RI-related applications.

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用于从目标离子中分离短寿命放射性同位素的3d打印设备。

在回旋加速器中产生的金属放射性同位素的分离是一个至关重要的过程。本报告描述了一种新设计的用于这种分离的3d打印设备的开发。3d打印制造方法为制造一次性设备提供了一种经济有效的方法。整个分离过程包括选择性螯合物的形成，目标离子的吸附，最后，紫外线辐射诱导金属配合物的分解。所有这些步骤都是在开发的设备中实现的。此外，这种新型系统可以处理含有溶解RI和目标的实际溶液体积（约10 mL），并且设计为一次性的。采用67Ga/Zn和89Zr/Y两种RI/目标体系对分离性能进行了评价。所开发的装置通过改变螯合物形成条件（即酸浓度）实现普遍分离。在没有目标污染的情况下，可以实现几乎定量的RI回收率，并且可以在30分钟内自动获得高纯度的RI溶液。因此，本文提出的通用且具有成本效益的分离装置适用于广泛的RI相关应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Applied Radiation and Isotopes 工程技术-核科学技术

CiteScore

3.00

自引率

12.50%

发文量

406

审稿时长

13.5 months

期刊介绍： Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.