Evaluating the thermal effects of Gaussian versus rectangular laser beams on single-layer biological tissues: Implications for advanced biomedical therapies

IF 5.8 2区 工程技术 Q1 ENGINEERING, MECHANICAL
Mohsan Hassan , Fateh Mebarek-Oudina , Edrisa Jawo , A.I. Ismail , M.M. Helal
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Abstract

This study explores the thermal dynamics of single-layer biological tissues subjected to Gaussian and rectangular laser beams, focusing on their unique thermal characteristics and potential medical applications. A comprehensive mathematical model that incorporates the Local Thermal Non-equilibrium (LTNE) framework is utilized, considering factors like tissue porosity and dual-lag effects to better understand thermal behavior. Through extensive numerical simulations, the influences of porosity, laser intensity, and exposure duration on the tissues under both beam configurations are analyzed. Results reveal that rectangular beams produce intense, localized heating, resulting in sharp temperature peaks that are particularly advantageous for targeted therapies. In contrast, Gaussian beams facilitate more uniform temperature distributions, which are beneficial for treatments requiring broader thermal coverage. Notably, it is found that increased porosity significantly mitigates maximum temperatures and reduces the extent of thermal damage, whereas higher laser intensities and prolonged exposure times lead to heightened tissue temperatures and an increased risk of thermal injury. These findings enhance the current understanding of bio-heat transfer mechanics and offer valuable guidance for the design and implementation of safer and more effective laser-based therapeutic systems.
评估高斯激光束与矩形激光束对单层生物组织的热效应:对先进生物医学治疗的意义
本研究探讨高斯和矩形激光束作用下单层生物组织的热动力学,重点研究其独特的热特性和潜在的医学应用。为了更好地理解热行为,我们采用了一个综合的数学模型,该模型结合了局部热不平衡(LTNE)框架,考虑了组织孔隙度和双滞后效应等因素。通过大量的数值模拟,分析了两种光束配置下孔隙度、激光强度和照射时间对组织的影响。结果表明,矩形光束产生强烈的局部加热,导致尖锐的温度峰值,这对靶向治疗特别有利。相比之下,高斯光束有助于更均匀的温度分布,这有利于需要更广泛的热覆盖的处理。值得注意的是,研究发现孔隙度的增加显著降低了最高温度,减少了热损伤的程度,而更高的激光强度和延长的暴露时间会导致组织温度升高,热损伤的风险增加。这些发现增强了目前对生物传热力学的理解,并为设计和实施更安全、更有效的激光治疗系统提供了有价值的指导。
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来源期刊
CiteScore
10.30
自引率
13.50%
发文量
1319
审稿时长
41 days
期刊介绍: International Journal of Heat and Mass Transfer is the vehicle for the exchange of basic ideas in heat and mass transfer between research workers and engineers throughout the world. It focuses on both analytical and experimental research, with an emphasis on contributions which increase the basic understanding of transfer processes and their application to engineering problems. Topics include: -New methods of measuring and/or correlating transport-property data -Energy engineering -Environmental applications of heat and/or mass transfer
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