Design and implementation of a low-cost gimbal-based angular ultrasound gantry for optimal tissue slice selection using deep learning

IF 2 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC
Abhishek Kumar, Akshay S. Menon, Divyansh Sharma, Raviteja Sista, Debdoot Sheet
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Abstract

Ultrasound (US) is a widely popular imaging technique for the diagnosis of tumors and associated soft tissue pathology. Traditionally, excised tumor masses are manually sliced for microscopic examination, which is a resource-intensive, time-consuming process, and prone to human error. The proposed work addresses these challenges by developing a cost-effective US gantry system integrated with a deep learning algorithm to automate the tissue slice selection process. This system scans the entire tumor and by integrating a deep learning algorithm predicts the optimal slice to assist its preparation for microscopic analysis. Automating this process reduces the time and resources required while minimizing the risk of human error. Optimal tissue slice reduces sampling associated uncertainty in diagnosis and treatment planning. Thereby determining tumor grade and type, and helping to reduce the treatment risks. The initial development focused on a linear US gantry that moves in one direction to acquire B-mode images. However, this design is limited, as it cannot fully capture the tumor’s structural complexity. In order to overcome this, we developed an angular US gantry that can maneuver along multiple angles, acquiring a broader range of images for comprehensive geometric analysis. The angular gantry demonstrated significant improvement, achieving 98% accuracy in selecting the optimal tissue slice.

Abstract Image

利用深度学习设计和实现低成本的基于云台的角度超声龙门,以实现最佳组织切片选择
超声(US)是一种广泛流行的成像技术,用于诊断肿瘤和相关的软组织病理。传统上,切除的肿瘤块是人工切片进行显微镜检查,这是一个资源密集、耗时的过程,而且容易出现人为错误。提出的工作通过开发具有成本效益的美国龙门系统集成深度学习算法来自动化组织切片选择过程来解决这些挑战。该系统扫描整个肿瘤,并通过集成深度学习算法来预测最佳切片,以帮助其为显微镜分析做准备。自动化此过程可以减少所需的时间和资源,同时最大限度地减少人为错误的风险。最佳组织切片减少了诊断和治疗计划中采样相关的不确定性。从而确定肿瘤的分级和类型,并有助于降低治疗风险。最初的开发集中在一个向一个方向移动的线性美国龙门架上,以获取b模式图像。然而,这种设计是有限的,因为它不能完全捕捉肿瘤的结构复杂性。为了克服这一问题,我们开发了一种有角度的美国龙门,可以沿着多个角度进行机动,获取更广泛的图像进行全面的几何分析。角度龙门在选择最佳组织切片方面有显著的改善,准确率达到98%。
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来源期刊
HardwareX
HardwareX Engineering-Industrial and Manufacturing Engineering
CiteScore
4.10
自引率
18.20%
发文量
124
审稿时长
24 weeks
期刊介绍: HardwareX is an open access journal established to promote free and open source designing, building and customizing of scientific infrastructure (hardware). HardwareX aims to recognize researchers for the time and effort in developing scientific infrastructure while providing end-users with sufficient information to replicate and validate the advances presented. HardwareX is open to input from all scientific, technological and medical disciplines. Scientific infrastructure will be interpreted in the broadest sense. Including hardware modifications to existing infrastructure, sensors and tools that perform measurements and other functions outside of the traditional lab setting (such as wearables, air/water quality sensors, and low cost alternatives to existing tools), and the creation of wholly new tools for either standard or novel laboratory tasks. Authors are encouraged to submit hardware developments that address all aspects of science, not only the final measurement, for example, enhancements in sample preparation and handling, user safety, and quality control. The use of distributed digital manufacturing strategies (e.g. 3-D printing) is encouraged. All designs must be submitted under an open hardware license.
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