Addressing the fungal diagnostic gap in LMICs

IF 103.3 1区生物学 Q1 MICROBIOLOGY

Nature Reviews Microbiology Pub Date : 2025-07-23 DOI:10.1038/s41579-025-01216-4

Felix Bongomin, David W. Denning

引用次数: 0

Abstract

The WHO fungal priority pathogens list exposes critical diagnostic gaps in low- and middle-income countries (LMICs), where limited access to rapid, affordable tests hinders timely treatment. To reduce mortality, LMICs must urgently invest in laboratory capacity, training and point-of-care diagnostics, especially for fungal diseases associated with HIV (cryptococcosis, Pneumocystis pneumonia and histoplasmosis), tuberculosis (chronic pulmonary aspergillosis), hospital-acquired candidiasis and the fungal neglected tropical diseases.

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解决中低收入国家真菌诊断差距问题

世卫组织真菌重点病原体清单暴露了低收入和中等收入国家在诊断方面的重大差距，这些国家获得快速、负担得起的检测的机会有限，阻碍了及时治疗。为了降低死亡率，低收入国家必须紧急投资于实验室能力、培训和即时诊断，特别是与艾滋病毒相关的真菌疾病（隐球菌病、肺囊虫病和组织浆菌病）、结核病（慢性肺曲霉病）、医院获得性念珠菌病与被忽视的热带真菌疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Microbiology 生物-微生物学

CiteScore

74.00

自引率

0.50%

发文量

149

审稿时长

6-12 weeks

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