Can the tumor neural niche be targeted to re-program cancer?

IF 7.2 1区生物学 Q1 Agricultural and Biological Sciences

PLoS Biology Pub Date : 2025-07-21 eCollection Date: 2025-07-01 DOI:10.1371/journal.pbio.3003266

Erica K Sloan, Joo Sang Lee

引用次数: 0

Abstract

Interactions between the peripheral nervous system and solid tumors influence cancer progression and treatment response. Defining the 3D tumor neural niche using spatial omics and AI technologies will identify new opportunities for targeted therapies to stop cancer progression.

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肿瘤神经龛能否成为癌症重编程的靶点？

周围神经系统和实体瘤之间的相互作用影响癌症的进展和治疗反应。利用空间组学和人工智能技术定义三维肿瘤神经龛将为靶向治疗找到新的机会，以阻止癌症的进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

PLoS Biology BIOCHEMISTRY & MOLECULAR BIOLOGY-BIOLOGY

CiteScore

15.40

自引率

2.00%

发文量

359

审稿时长

3-8 weeks

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