Evidence on vaping e-cigarettes as a risk factor for cancer: A systematic review

IF 2 Q3 HEALTH POLICY & SERVICES
Guilherme Guedes de Oliveira , Rebeca Milka Lemos Magalhães Liberato , Amaxsell Thiago Barros de Souza , Ayane Cristine Alves Sarmento , Edilmar de Moura Santos , Kleyton Santos de Medeiros , Irami Araújo Filho
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引用次数: 0

Abstract

Objective

This review aims to evaluate the association between e-cigarette use and cancer risk.

Study design

A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.

Methods

Studies were sourced from PubMed/MEDLINE, LILACS, Embase, Web of Science, and Scopus up to September 2024. Observational studies evaluating the association between e-cigarette use and cancer risk were included. Data selection and extraction were performed independently and in pairs. The risk of bias was assessed using the Newcastle-Ottawa Scale (NOS) for cohort and case-control studies and the Joanna Briggs Institute (JBI) critical appraisal tool for cross-sectional studies.

Results

Ten studies were included in the final analysis, a total of 143,975 patients. Skin cancer represented 7 % (n = 635) of cases, followed by breast cancer at 4 % (n = 370), prostate cancer at 2 % (n = 234), melanoma at 1.4 % (n = 118), and colon cancer 1.2 % (n = 106). A single study identified associations between e-cigarette use and various types of cancer, along with links to lung disease, depression, and physical inactivity. Another study suggested a potential association between e-cigarette use and lung cancer, as well as a later-stage diagnosis for breast and colorectal cancers. However, three studies found no significant link between e-cigarette use and non–muscle-invasive bladder cancer.

Conclusion

E-cigarette use may be associated with an increased risk of certain cancers, including cervical and breast cancer. However, the evidence remains inconclusive, and more rigorous longitudinal studies are needed to provide clearer conclusions.
吸电子烟是癌症风险因素的证据:一项系统综述。
目的:本综述旨在评估电子烟使用与癌症风险之间的关系。研究设计:根据系统评价和荟萃分析的首选报告项目(PRISMA)声明进行系统评价。方法:研究来源于PubMed/MEDLINE、LILACS、Embase、Web of Science和Scopus,截止到2024年9月。其中包括评估电子烟使用与癌症风险之间关系的观察性研究。数据的选择和提取是独立或成对进行的。对队列研究和病例对照研究使用纽卡斯尔-渥太华量表(NOS)评估偏倚风险,对横断面研究使用乔安娜布里格斯研究所(JBI)关键评估工具。结果:10项研究纳入最终分析,共143975例患者。皮肤癌占7% (n = 635),其次是乳腺癌4% (n = 370),前列腺癌2% (n = 234),黑色素瘤1.4% (n = 118),结肠癌1.2% (n = 106)。一项单独的研究发现了电子烟的使用与各种类型的癌症之间的联系,以及与肺部疾病、抑郁症和缺乏身体活动的联系。另一项研究表明,电子烟的使用与肺癌以及乳腺癌和结直肠癌的晚期诊断之间存在潜在关联。然而,三项研究发现电子烟的使用与非肌肉侵袭性膀胱癌之间没有明显的联系。结论:电子烟的使用可能与某些癌症的风险增加有关,包括宫颈癌和乳腺癌。然而,证据仍然不确定,需要更严格的纵向研究来提供更清晰的结论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Cancer Policy
Journal of Cancer Policy Medicine-Health Policy
CiteScore
2.40
自引率
7.70%
发文量
47
审稿时长
65 days
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