New Contours, Different Risks: A 9-Year Comparison of Trends and Postoperative Complications in Patients Undergoing Aesthetic Surgery With Prior Bariatric Surgery vs Glucagon-Like Peptide 1 Receptor Agonist Use.

IF 3 2区医学 Q1 SURGERY

Aesthetic Surgery Journal Pub Date : 2025-07-22 DOI:10.1093/asj/sjaf131

Jeffrey Khong, Rachana Suresh, Kitae E Park, Hooman Soltanian

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引用次数: 0

Abstract

Background: The significant weight loss associated with bariatric surgery and glucagon-like peptide 1 receptor agonist (GLP-1 RA) use often prompts patients to seek aesthetic procedures to address changes in skin tightness and body contours.

Objectives: We sought to examine trends in aesthetic surgery utilization and postoperative complication rates between these two patient populations.

Methods: Using the TriNetX database, we identified patients undergoing aesthetic procedures between 2016-2024 and stratified cohorts based on prior bariatric surgery or GLP-1 RA use. Mean annual growth rates between groups were compared using least-squares means with post-hoc Tukey tests. Postoperative 90-day complication rates including hematoma, seroma, infection, wound dehiscence, DVT/PE, emergency department utilization, readmissions, and mortality were evaluated using risk ratios after propensity score matching.

Results: Between 2016-2021, the mean annual growth rate aesthetic procedures among GLP-1 RA users was 36.1% per year, compared to 27.1% among post-bariatric patients (p=0.0026). After 2021, the mean annual growth rate aesthetic procedures increased to 53.8% (+17.7%, 95% CI: [10.4%, 25.4%]) for GLP-1 RA users and declined to -4% (-31.1%, 95% CI: [-37.7%, -25.5%]) for post-bariatric surgery patients. After matching, bariatric surgery patients had higher risk of hematoma (RR: 1.99; CI: [1.10, 3.62], p<0.05), infections (RR: 1.37; CI: [1.01, 1.88], p<0.05), and emergency department use (RR: 1.54; CI: [1.05, 2.26], p<0.05).

Conclusions: Aesthetic surgery utilization is sharply increasing among patients with prior GLP-1 RA use compared to post-bariatric surgery patients. Postsurgical hematoma, infection, and emergency department utilization were greater in post-bariatric patients. Future studies are needed to investigate underlying factors.

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新的轮廓，不同的风险：既往减肥手术与使用胰高血糖素样肽1受体激动剂进行美容手术患者的9年趋势和术后并发症的比较

背景：与减肥手术和胰高血糖素样肽1受体激动剂（GLP-1 RA）的使用相关的显著体重减轻通常促使患者寻求美容手术来解决皮肤紧绷和身体轮廓的变化。目的：我们试图研究这两种患者群体在美容手术应用和术后并发症发生率方面的趋势。方法：使用TriNetX数据库，我们根据先前的减肥手术或GLP-1 RA使用情况，确定了2016-2024年间接受美容手术的患者和分层队列。组间平均年增长率采用最小二乘法和事后Tukey检验进行比较。术后90天的并发症发生率，包括血肿、血肿、感染、伤口裂开、DVT/PE、急诊科使用率、再入院率和死亡率，采用倾向评分匹配后的风险比进行评估。结果：2016-2021年间，GLP-1 RA使用者美容手术的平均年增长率为36.1%，而减肥后患者为27.1% （p=0.0026）。2021年后，GLP-1 RA使用者的美容手术平均年增长率增加到53.8% (+17.7%,95% CI:[10.4%, 25.4%])，而减肥手术后患者的美容手术平均年增长率下降到-4% （-31.1%,95% CI:[-37.7%, -25.5%]）。配对后，减肥手术患者发生血肿的风险较高(RR: 1.99；CI: [1.10, 3.62]， p结论：与减肥手术后的患者相比，先前使用GLP-1 RA的患者的美容手术使用率急剧增加。术后血肿、感染和急诊科使用率在减肥后患者中更高。未来的研究需要调查潜在的因素。

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来源期刊

Aesthetic Surgery Journal SURGERY-

CiteScore

6.20

自引率

20.70%

发文量

309

审稿时长

6-12 weeks

期刊介绍： Aesthetic Surgery Journal is a peer-reviewed international journal focusing on scientific developments and clinical techniques in aesthetic surgery. The official publication of The Aesthetic Society, ASJ is also the official English-language journal of many major international societies of plastic, aesthetic and reconstructive surgery representing South America, Central America, Europe, Asia, and the Middle East. It is also the official journal of the British Association of Aesthetic Plastic Surgeons, the Canadian Society for Aesthetic Plastic Surgery and The Rhinoplasty Society.