Integration of Digital Cytology in Quality Assurance Programs for Cytopathology.

Abstract

Quality assurance (QA) and quality control (QC) in cytopathologic practice are key elements in ensuring high-standard diagnostic services. Recently, the implementation of digital cytology (DC) has led to fundamental changes in the cytopathology workflow. Primary diagnosis using DC, consultations via cloud-based DC platforms, and rapid on-site evaluations through telecytopathology are gradually increasing in clinical practice. These technological advances necessitate a forward-thinking, conceptual transition and redefinition of QA and QC in the era of DC. In this review, we will explore various aspects of QA and QC activities, focusing on the role of DC as a QC measure and the development of QA and QC protocols specific to DC systems. We will cover practical approaches to utilizing DC for traditional QA and QC activities, including the education and training of laboratory personnel and cytopathologists, as well as digital proficiency testing through cloud-based platforms. Additionally, we will discuss current international recommendations for implementing DC in cytopathologic practice and outline strategies for the efficient and safe management of DC environments. Through these considerations, DC will become an essential part of QA/QC programs in cytopathology, providing a foundation for more accurate and reliable diagnostic practices.