Front Cover: β1,6-Selective Enzymatic N-Acetylglucosamination Catalyzed by the Family GH84 N-Acetyl-β-D-glucosaminidase from Bacteroides thetaiotaomicron and its Glycosyl Acceptor Specificity (Chem. Asian J. 14/2025)

IF 3.5 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemistry - An Asian Journal Pub Date : 2025-07-22 DOI:10.1002/asia.202581401

Rika Okuno, Shunsuke Nakada, Kisuke Tonomura, Yuji Aso, Daijiro Takeshita, Takayuki Ohnuma, Tomonari Tanaka

引用次数: 0

Abstract

This cover picture illustrates enzymatic glycosylation for the synthesis of the O-glycan core 6 disaccharide moiety, GlcNAcβ1-6GalNAc. The β1,6-selective N-acetylglucosamination was catalyzed by an N-acetyl-β-D-glucosaminidase from Bacteroides thetaiotaomicron with an N-acetyl-D-glucosamine (GlcNAc) oxazoline derivative as the glycosyl donor, resulting in disaccharides with β1,6-linked GlcNAc. More details can be found in article number e202500142 by Tomonari Tanaka, Takayuki Ohnuma, and co-workers.

Abstract Image

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前封面：拟杆菌（Bacteroides thetaotaomicron） GH84家族n -乙酰-β- d -氨基葡萄糖酶催化的β1,6选择性酶n -乙酰氨基葡萄糖化及其糖基受体特异性（Chem.）。亚洲J. 14/2025)

这张封面图片说明了o -聚糖核心6双糖部分GlcNAcβ1-6GalNAc的酶糖基化合成。以n -乙酰- d -氨基葡萄糖（GlcNAc）恶唑啉衍生物为糖基供体，利用拟杆菌（Bacteroides thetaiotamicron）中的n -乙酰-β- d -氨基葡萄糖酶催化β1,6选择性n -乙酰氨基葡萄糖氨基化反应，得到β1,6-连接GlcNAc的双糖。更多细节可以在Tomonari Tanaka， Takayuki Ohnuma及其同事的文章编号e202500142中找到。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemistry - An Asian Journal 化学-化学综合

CiteScore

7.00

自引率

2.40%

发文量

535

审稿时长

1.3 months

期刊介绍： Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics. Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews. A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal. Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).