A Comprehensive Review of Nanotechnology Based Nanoemulsion Delivery Systems for Targeted Drug Delivery and Enhanced Therapeutic Efficacy.

Q2 Pharmacology, Toxicology and Pharmaceutics

Pharmaceutical nanotechnology Pub Date : 2025-07-17 DOI:10.2174/0122117385388338250711001010

Mukesh Kumar, Divya Pathak

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Abstract

Herbal medicine has been a cornerstone of traditional healthcare for centuries, offering a wide array of bioactive compounds derived from plants. However, its efficacy is often limited by poor bioavailability, instability, and non-targeted delivery. Recent advancements in nanotechnology have provided innovative solutions to these challenges through developing nanoemulsion delivery systems. These systems enhance the solubility and stability of herbal extracts, ensuring targeted delivery to specific tissues or cells. Nanocarriers such as liposomes, solid lipid nanoparticles, and polymeric nanoparticles can encapsulate bioactive compounds, protecting them from degradation and facilitating controlled release. This approach not only improves therapeutic outcomes but also reduces side effects by minimizing exposure to non-targeted areas. Furthermore, nanotechnology allows for personalized medicine by tailoring nanocarriers to individual patient needs, enhancing treatment efficacy and compliance. The integration of nanotechnology with herbal medicine holds significant potential for revolutionizing healthcare by providing more effective and targeted treatments for various diseases, including cancer, neurological disorders, and cardiovascular diseases.

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基于纳米技术的靶向药物递送和增强治疗效果的纳米乳递送系统综述。

几个世纪以来，草药一直是传统医疗保健的基石，它提供了一系列从植物中提取的生物活性化合物。然而，其疗效往往受到生物利用度差、不稳定和非靶向给药的限制。纳米技术的最新进展通过开发纳米乳液输送系统为这些挑战提供了创新的解决方案。这些系统提高了草药提取物的溶解度和稳定性，确保靶向递送到特定组织或细胞。纳米载体如脂质体、固体脂质纳米颗粒和聚合物纳米颗粒可以包裹生物活性化合物，保护它们免受降解并促进控制释放。这种方法不仅提高了治疗效果，而且通过最大限度地减少非靶向区域的暴露，减少了副作用。此外，纳米技术允许个性化医疗，通过定制纳米载体，以个别病人的需要，提高治疗效果和依从性。纳米技术与草药的结合为各种疾病，包括癌症、神经系统疾病和心血管疾病，提供更有效和更有针对性的治疗方法，具有革新医疗保健的巨大潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pharmaceutical nanotechnology Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

4.20

自引率

0.00%

发文量

期刊介绍： Pharmaceutical Nanotechnology publishes original manuscripts, full-length/mini reviews, thematic issues, rapid technical notes and commentaries that provide insights into the synthesis, characterisation and pharmaceutical (or diagnostic) application of materials at the nanoscale. The nanoscale is defined as a size range of below 1 µm. Scientific findings related to micro and macro systems with functionality residing within features defined at the nanoscale are also within the scope of the journal. Manuscripts detailing the synthesis, exhaustive characterisation, biological evaluation, clinical testing and/ or toxicological assessment of nanomaterials are of particular interest to the journal’s readership. Articles should be self contained, centred around a well founded hypothesis and should aim to showcase the pharmaceutical/ diagnostic implications of the nanotechnology approach. Manuscripts should aim, wherever possible, to demonstrate the in vivo impact of any nanotechnological intervention. As reducing a material to the nanoscale is capable of fundamentally altering the material’s properties, the journal’s readership is particularly interested in new characterisation techniques and the advanced properties that originate from this size reduction. Both bottom up and top down approaches to the realisation of nanomaterials lie within the scope of the journal.