¹⁸F-FAPI-04 PET/CT Imaging of Rare Brain Metastasis from Myxoid Pleomorphic Liposarcoma.

IF 2.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Nuclear Medicine and Molecular Imaging Pub Date : 2025-08-01 Epub Date: 2025-01-06 DOI:10.1007/s13139-024-00901-1

Yong Wang, Kelin Wang, Dongfang Meng, Kai Teng, Zhiguo Liu, Man Hu

引用次数: 0

Abstract

This study reports the first case of solitary brain metastasis from myxoid pleomorphic liposarcoma (MPLS) evaluated using ¹⁸F-FAPI-04 PET/CT. The imaging revealed a distinct "Halo Sign," reflecting the infiltration characteristics of cancer-associated fibroblasts (CAFs) within this rare tumor type. These findings highlight the utility of ¹⁸F-FAPI-04 PET/CT in characterizing tumor heterogeneity and underscore its potential to improve the diagnosis of rare brain metastases while informing future therapeutic strategies.

查看原文本刊更多论文

18F-FAPI-04罕见黏液样多形性脂肪肉瘤脑转移的PET/CT成像。

本研究报告首例黏液样多形性脂肪肉瘤（MPLS）单发脑转移的病例，采用18F-FAPI-04 PET/CT进行评估。成像显示明显的“晕征”，反映了这种罕见肿瘤类型中癌症相关成纤维细胞（CAFs）的浸润特征。这些发现强调了18F-FAPI-04 PET/CT在表征肿瘤异质性方面的效用，并强调了其在改善罕见脑转移诊断方面的潜力，同时为未来的治疗策略提供了信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nuclear Medicine and Molecular Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

2.20

自引率

7.70%

发文量

期刊介绍： Nuclear Medicine and Molecular Imaging (Nucl Med Mol Imaging) is an official journal of the Korean Society of Nuclear Medicine, which bimonthly publishes papers on February, April, June, August, October, and December about nuclear medicine and related sciences such as radiochemistry, radiopharmacy, dosimetry and pharmacokinetics / pharmacodynamics of radiopharmaceuticals, nuclear and molecular imaging analysis, nuclear and molecular imaging instrumentation, radiation biology and radionuclide therapy. The journal specially welcomes works of artificial intelligence applied to nuclear medicine. The journal will also welcome original works relating to molecular imaging research such as the development of molecular imaging probes, reporter imaging assays, imaging cell trafficking, imaging endo(exo)genous gene expression, and imaging signal transduction. Nucl Med Mol Imaging publishes the following types of papers: original articles, reviews, case reports, editorials, interesting images, and letters to the editor. The Korean Society of Nuclear Medicine (KSNM) KSNM is a scientific and professional organization founded in 1961 and a member of the Korean Academy of Medical Sciences of the Korean Medical Association which was established by The Medical Services Law. The aims of KSNM are the promotion of nuclear medicine and cooperation of each member. The business of KSNM includes holding academic meetings and symposia, the publication of journals and books, planning and research of promoting science and health, and training and qualification of nuclear medicine specialists.

18F-FAPI-04 PET/CT Imaging of Rare Brain Metastasis from Myxoid Pleomorphic Liposarcoma.

Abstract

¹⁸F-FAPI-04 PET/CT Imaging of Rare Brain Metastasis from Myxoid Pleomorphic Liposarcoma.