Sensitizations to aeroallergens in Israel: Prevalences and profiles.

IF 2.1 4区医学 Q3 ALLERGY

Allergologia et immunopathologia Pub Date : 2025-07-01 eCollection Date: 2025-01-01 DOI:10.15586/aei.v53i4.1335

Menachem Rottem, Mahmoud Noujedat, Youssef Awni

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引用次数: 0

Abstract

Background: Most of the literature on aeroallergen sensitization have been generated in North America and Western Europe.

Objectives: To determine aeroallergen sensitization prevalences and patterns among patients with physician-diagnosed allergic rhinitis (AR) in Israel.

Methods: We conducted a retrospective, observational study of sensitization to 20 aeroallergen extracts in skin prick tests (SPTs) among consecutive pediatric and adult patients with AR attending the allergy clinic at Emek Medical Center (Afula, Israel) and an affiliated regional outpatient clinic (Nazareth, Israel) from 2021 to 2023.

Results: A total of 1993 patients (547 females, 27.4%) were included (median [range] age: 24 [6-82]). The five allergens or groups of allergens with the highest SPT positivity rates were house dust mite (HDM: Dermatophagoides pteronyssinus and D. farinae; 74.8%), tree pollens (44.3%), olive pollen (34.1%), grass pollens (25.6%), and cat dander (22.6%). Of the 1993 patients, 947 (47.5%) had a positive SPT for just one of the 20 tested extracts. Patients sensitized to cat dander were significantly (12-fold) more likely to be sensitized to dog dander and vice versa. Patients living in an urban environment were more likely to be sensitized to cypress pollen (19.3% vs. 12.0% in a nonurban environment; p = 0.002, chi-squared test) and pellitory pollen (21.6% vs. 15.1%, respectively; p = 0.010, chi-squared test). Our suggestion is that in the Middle East, patients with symptoms of AR can be effectively screened with a standard "European" panel of allergen extracts for SPTs (such as that suggested by the Global Allergy and Asthma European Network [GA2LEN] organization), plus Johnson grass, Bermuda grass, and oak and eucalyptus pollen extracts.

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以色列的空气过敏原致敏：患病率和概况。

背景：大多数关于空气过敏原致敏的文献来自北美和西欧。目的：确定以色列医生诊断的变应性鼻炎（AR）患者的空气过敏原致敏率和模式。方法：我们对2021年至2023年在Emek医疗中心（Afula，以色列）和附属地区门诊（拿撒勒，以色列）就诊的连续儿科和成人AR患者进行了一项回顾性观察性研究，观察皮肤点刺试验（SPTs）中对20种空气过敏原提取物的致敏性。结果：共纳入1993例患者，其中女性547例，占27.4%（中位年龄：24岁[6-82岁]）。SPT阳性率最高的5组过敏原分别为房尘螨（HDM: Dermatophagoides pteronyssinus）和粉螨（D. farinae）；74.8%)、树木花粉（44.3%）、橄榄花粉（34.1%）、草花粉（25.6%）和猫皮屑（22.6%）。在1993例患者中，947例（47.5%）仅对20种测试提取物中的一种有阳性的SPT。对猫皮屑敏感的患者对狗皮屑敏感的可能性显著增加（12倍），反之亦然。生活在城市环境中的患者更有可能对柏树花粉敏感（19.3%比12.0%）；P = 0.002，卡方检验)和花瓣花粉(21.6% vs. 15.1%；P = 0.010，卡方检验)。我们的建议是，在中东地区，有AR症状的患者可以通过标准的“欧洲”过敏原提取物（如全球过敏和哮喘欧洲网络[GA2LEN]组织所建议的），加上约翰逊草、百慕大草、橡树和桉树花粉提取物，有效地筛查出spt的过敏原提取物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Allergologia et immunopathologia 医学-过敏

CiteScore

3.70

自引率

0.00%

发文量

131

审稿时长

6-12 weeks

期刊介绍： Founded in 1972 by Professor A. Oehling, Allergologia et Immunopathologia is a forum for those working in the field of pediatric asthma, allergy and immunology. Manuscripts related to clinical, epidemiological and experimental allergy and immunopathology related to childhood will be considered for publication. Allergologia et Immunopathologia is the official journal of the Spanish Society of Pediatric Allergy and Clinical Immunology (SEICAP) and also of the Latin American Society of Immunodeficiencies (LASID). It has and independent international Editorial Committee which submits received papers for peer-reviewing by international experts. The journal accepts original and review articles from all over the world, together with consensus statements from the aforementioned societies. Occasionally, the opinion of an expert on a burning topic is published in the "Point of View" section. Letters to the Editor on previously published papers are welcomed. Allergologia et Immunopathologia publishes 6 issues per year and is included in the major databases such as Pubmed, Scopus, Web of Knowledge, etc.