Lucas S. Ribeiro, João Rocha Maia, Vítor M. Gaspar, Catarina A. Custódio, Emerson R. Camargo, Rita Sobreiro-Almeida, João F. Mano
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Abstract
This study explores the availability and intrinsic bioactivity of blood-derived proteins, namely human platelet lysates (hPL), for developing granular bioinks. Bulk hydrogels are generated from pristine/photo-responsive hPL following their mechanical granularization, and microgel jamming. It provides novel insights into rheological requirements and jamming methodologies of patient-derived products, where nozzle jamming outperformed, accounting for its simplicity and reproducible outcomes (e70041).
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