I Skrypnyk, G Maslova, T Lymanets, I Gusachenko, G Yeroshenko
{"title":"RARE CASE OF CD10+CD23+ HAIRY CELL LEUKEMIA WITH LEUKOCYTOSIS. CASE REPORT AND LITERATURE REVIEW.","authors":"I Skrypnyk, G Maslova, T Lymanets, I Gusachenko, G Yeroshenko","doi":"10.15407/exp-oncology.2025.01.091","DOIUrl":null,"url":null,"abstract":"<p><p>A rare case of hairy cell leukemia with CD10+CD23+ expression and leukocytosis is described. The key point marker for hairy cell leukemia is the presence of the BRAF V600E mutation regardless of the leukocyte count and atypical aberrant CD10+ or CD23+ expression. The presented clinical case report is important for understanding the biology of hairy cell leukemia and emphasizes the role of molecular genetic testing in atypical morpho-phenotyping disease presentation.</p>","PeriodicalId":94318,"journal":{"name":"Experimental oncology","volume":"47 1","pages":"91-95"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimental oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15407/exp-oncology.2025.01.091","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A rare case of hairy cell leukemia with CD10+CD23+ expression and leukocytosis is described. The key point marker for hairy cell leukemia is the presence of the BRAF V600E mutation regardless of the leukocyte count and atypical aberrant CD10+ or CD23+ expression. The presented clinical case report is important for understanding the biology of hairy cell leukemia and emphasizes the role of molecular genetic testing in atypical morpho-phenotyping disease presentation.
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