Using Convoluted Neural Networks in Diagnosing Lung Cancer on Computed Tomography Scans.

Current health sciences journal Pub Date : 2025-01-01 Epub Date: 2025-03-31 DOI:10.12865/CHSJ.51.01.09
Ovidiu Cîmpeanu, Ilona Mihaela Liliac, Mădălin Mămuleanu, Ștefan-Vlad Voinea, Mihai Olteanu, Costin-Teodor Streba
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Abstract

Introduction: Lung cancer represents a major health issue of the modern world, accounting for both most new cases and highest mortality rates worldwide. Early diagnosis and treatment remain essential in managing the disease; therefore, developing novel computer-assisted tools for processing large quantities of imaging data can prove indispensable. Our aim was to develop a novel convoluted neural network (CNN) to classify lung computed tomography (CT) images of suspect nodules.

Materials and methods: After obtaining ethical clearance, we included consenting patients with a lung mass found on a chest radiography, visible lung tumor on computer tomography and positive pathology or follow-up. After data augmentation, we trained a deep learning model to classify input images into two classes, malignant or benign. We evaluated the model by calculating accuracy, recall and precision.

Results: We successfully enrolled 176 patients from a total of 192 cases. Most were male (135 cases, accounting for 76.7%) and came from urban areas (111 cases, 63%). Most tumors were found on the right lung (103 cases). The model performed well on an imbalanced dataset, with recall values at 79.31%, while precision reached 62.16%, a training accuracy of 76.34% and a validation accuracy of 77.01%.

Conclusions: We proved that a CNN model can easily be implemented on regular hardware to successfully classify malignant and benign lung lesions on CT images. Future CNN implementations can greatly improve the imaging diagnosis of lung lesions; however, the physicians should always decide the medical management.

卷积神经网络在肺癌ct诊断中的应用。
肺癌是现代世界的一个主要健康问题,占全世界新病例最多和死亡率最高。早期诊断和治疗对于控制该病仍然至关重要;因此,开发新的计算机辅助工具来处理大量的成像数据是必不可少的。我们的目的是开发一种新的卷积神经网络(CNN)来对可疑结节的肺部计算机断层扫描(CT)图像进行分类。材料和方法:在获得伦理许可后,我们纳入了胸片上发现肺肿块,计算机断层扫描上可见肺肿瘤,病理或随访阳性的同意患者。在数据增强后,我们训练了一个深度学习模型,将输入的图像分为恶性和良性两类。我们通过计算准确率、查全率和查准率来评估模型。结果:我们从192例患者中成功招募了176例患者。以男性为主(135例,占76.7%),以城镇为主(111例,占63%)。多数肿瘤位于右肺(103例)。该模型在不平衡数据集上表现良好,召回率为79.31%,准确率为62.16%,训练准确率为76.34%,验证准确率为77.01%。结论:我们证明了CNN模型可以很容易地在常规硬件上实现,可以成功地对CT图像上的肺良恶性病变进行分类。未来的CNN实现可以大大提高肺部病变的影像学诊断;然而,医疗管理始终应由医生来决定。
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