"Sandwich" Technique for the Management of Chronic and Hemorrhagic Cervicitis Vs Antibiotics Alone: a Case-Control Clinical Study.

Abstract

Objectives: Cervicitis is commonly caused by sexually transmitted infections. This study compares the standard antibiotic treatment with antibiotics plus cryocoagulation in cases of chronic and hemorrhagic cervicitis. Although antibiotics are typically the first line of treatment, persistent cases often require additional interventions, like cryosurgery to obtain a cure. Material and method: Fifty women (mean age 38 years) with chronic cervicitis - based on clinical evaluations, cytology and vaginal culture - were enrolled in the present study. Twenty three participants were treated with combination therapy consisting of an initial course of antibiotics, followed by cryocoagulation and a subsequent round of antibiotics post-procedure, using a "sandwich" technique, while 27 subjects received antibiotics alone. Results:Our study showed that the "sandwich" technique achieved a success rate of 76.2% (p<0.005) after a single session for treating chronic cervicitis and hemorrhagic cervicitis (normalization in Pap smear) and 95.7% (p<0.05) success rate in clinical improvement after intervention. Conclusions: The combination of antibiotic treatment followed by cryosurgery and then another prophylactic course of antibiotics presents a promising approach for managing chronic cervicitis and recurrent cervical hemorrhage.