Associations of Abdominal Obesity-Related Dietary Patterns with Prediabetes and Type 2 Diabetes: Exploring the Mediating Effects of Body Composition and Altitude in Tibetan Adults.
Bin Zhang, Ruihua Xu, Zumin Shi, Tingting Wang, Wenxiu Jian, Haijing Wang, Ruijie Xu, Lei Zhao, Youfa Wang, Wen Peng
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引用次数: 0
Abstract
Objectives: To investigate the association of dietary patterns (DPs) with prediabetes and Type 2 Diabetes among Tibetan adults, first to identify DPs associated with abdominal obesity and examine their relationships with prediabetes and type 2 diabetes. Additionally, the study aims to investigate the mediating effects of body fat distribution and altitude on the associations between these DPs and the prevalence of prediabetes and Type 2 Diabetes.
Design: An open cohort among Tibetans.
Setting: Community-based.
Participants: The survey recruited 1003 participants registered for health check-ups from November to December 2018, and 1611 participants from December 2021 to May 2022. During the baseline and follow-up data collection, 1818 individuals participated in at least one of the two surveys, with 515 of them participating in both.
Results: Two DPs were identified by reduced rank regression (RRR). DP1 had high consumption of beef and mutton, non-caloric drink, offal, and low intake in tubers and roots, salty snacks, onion and spring onion, fresh fruits, desserts and nuts and seeds; DP2 had high intake of whole grains, Tibetan cheese, light-colored vegetables and pork and low of sugar-sweetened beverages, whole-fat dairy and poultry. Individuals in the highest tertile of DP1 showed higher risks of prediabetes (OR 95% CI) 1.35 (1.05, 1.73) and T2D 1.36 (1.05, 1.76). In the highest tertile of DP2 exhibited an elevated risk of T2D 1.63 (1.11, 2.40) in fully adjustment.
Conclusion: Abdominal adiposity-related DPs are positively associated with T2D. Promoting healthy eating should be considered to prevent T2D among Tibetan adults.
期刊介绍：
Public Health Nutrition provides an international peer-reviewed forum for the publication and dissemination of research and scholarship aimed at understanding the causes of, and approaches and solutions to nutrition-related public health achievements, situations and problems around the world. The journal publishes original and commissioned articles, commentaries and discussion papers for debate. The journal is of interest to epidemiologists and health promotion specialists interested in the role of nutrition in disease prevention; academics and those involved in fieldwork and the application of research to identify practical solutions to important public health problems.
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