Drug efficacy and safety of azithromycin combined with pulmonary physical therapy for bacterial pneumonia in children.

IF 0.7 4区 医学 Q4 PHARMACOLOGY & PHARMACY
Lingxiao Shi, Yangjin Chen, Huidan Yang, Shuai Wei
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引用次数: 0

Abstract

The drug effect and safety of azithromycin combined with lung physical therapy in the treatment of bacterial pneumonia in children were studied. A total of 112 cases were selected and divided into a study group and a control group with 56 cases in each group. The control group used azithromycin and the study group received assisted lung physical therapy. The drug effects, symptom disappearance time, inflammatory factors, lung function indicators and adverse reaction incidence of the two groups were compared. The results showed that the drug effect of the study group was higher than that of the control group, the level of inflammatory factors was lower than that of the control group, the symptom disappearance time was shorter and the lung function indicators were better. The incidence of adverse drug reactions in the two groups was comparable. Using the same drug azithromycin, under the action of pulmonary physical therapy, azithromycin can better exert its efficacy without affecting the safety of the drug.

阿奇霉素联合肺部物理治疗儿童细菌性肺炎的疗效和安全性。
观察阿奇霉素联合肺部物理疗法治疗儿童细菌性肺炎的疗效和安全性。选取112例病例,分为研究组和对照组,每组56例。对照组给予阿奇霉素治疗,研究组给予辅助肺物理治疗。比较两组患者的用药效果、症状消失时间、炎症因子、肺功能指标及不良反应发生率。结果显示,研究组用药效果高于对照组,炎症因子水平低于对照组,症状消失时间较短,肺功能指标较好。两组药物不良反应发生率具有可比性。使用同一种药物阿奇霉素,在肺部物理治疗的作用下,阿奇霉素可以更好地发挥其功效,而不影响药物的安全性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.40
自引率
12.50%
发文量
211
审稿时长
4.5 months
期刊介绍: Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013. PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.
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