{"title":"Drug efficacy and safety of azithromycin combined with pulmonary physical therapy for bacterial pneumonia in children.","authors":"Lingxiao Shi, Yangjin Chen, Huidan Yang, Shuai Wei","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The drug effect and safety of azithromycin combined with lung physical therapy in the treatment of bacterial pneumonia in children were studied. A total of 112 cases were selected and divided into a study group and a control group with 56 cases in each group. The control group used azithromycin and the study group received assisted lung physical therapy. The drug effects, symptom disappearance time, inflammatory factors, lung function indicators and adverse reaction incidence of the two groups were compared. The results showed that the drug effect of the study group was higher than that of the control group, the level of inflammatory factors was lower than that of the control group, the symptom disappearance time was shorter and the lung function indicators were better. The incidence of adverse drug reactions in the two groups was comparable. Using the same drug azithromycin, under the action of pulmonary physical therapy, azithromycin can better exert its efficacy without affecting the safety of the drug.</p>","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 3","pages":"939-944"},"PeriodicalIF":0.7000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan journal of pharmaceutical sciences","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
The drug effect and safety of azithromycin combined with lung physical therapy in the treatment of bacterial pneumonia in children were studied. A total of 112 cases were selected and divided into a study group and a control group with 56 cases in each group. The control group used azithromycin and the study group received assisted lung physical therapy. The drug effects, symptom disappearance time, inflammatory factors, lung function indicators and adverse reaction incidence of the two groups were compared. The results showed that the drug effect of the study group was higher than that of the control group, the level of inflammatory factors was lower than that of the control group, the symptom disappearance time was shorter and the lung function indicators were better. The incidence of adverse drug reactions in the two groups was comparable. Using the same drug azithromycin, under the action of pulmonary physical therapy, azithromycin can better exert its efficacy without affecting the safety of the drug.
期刊介绍:
Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013.
PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.