Clinical study on preventive treatment of postpartum hemorrhage with carboprost tromethamine combined with oxytocin and misoprostol.

IF 0.7 4区 医学 Q4 PHARMACOLOGY & PHARMACY
Jie Jiao, Lei Li, LiYang Liu, ChunYan Huang
{"title":"Clinical study on preventive treatment of postpartum hemorrhage with carboprost tromethamine combined with oxytocin and misoprostol.","authors":"Jie Jiao, Lei Li, LiYang Liu, ChunYan Huang","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>To study the clinical effect of carboprost tromethamine combined with oxytocin and misoprostol in the preventive treatment of postpartum hemorrhage. 94 cases of postpartum hemorrhage patients from October, 2022 to October, 2023 were divided into the reference group (treated with oxytocin and misoprostol) and the observation group (treated with carboprost tromethamine, oxytocin and misoprostol) and the treatment situation was analyzed. Compared with the reference group, the stress and serum indexes in the observation group were significantly decreased. Except oxygen saturation, the postpartum hemorrhage and hemostasis time in the observation group were significantly lower than those in the reference group and the hemoglobin content was relatively high. After treatment, the improvement of coagulation function in the observation group was better than that in the reference group. The incidence of complications was 21.28% in the reference group and 4.26% in the observation group, the difference was statistically significant (P < 0.05). In the preventive treatment of postpartum hemorrhage, triple medication is more effective, which can improve patients' stress response and serum indexes, reduce the amount of bleeding and improve patients' coagulation function. At the same time, it is also very beneficial to control complications and has high safety.</p>","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 3","pages":"1023-1027"},"PeriodicalIF":0.7000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan journal of pharmaceutical sciences","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0

Abstract

To study the clinical effect of carboprost tromethamine combined with oxytocin and misoprostol in the preventive treatment of postpartum hemorrhage. 94 cases of postpartum hemorrhage patients from October, 2022 to October, 2023 were divided into the reference group (treated with oxytocin and misoprostol) and the observation group (treated with carboprost tromethamine, oxytocin and misoprostol) and the treatment situation was analyzed. Compared with the reference group, the stress and serum indexes in the observation group were significantly decreased. Except oxygen saturation, the postpartum hemorrhage and hemostasis time in the observation group were significantly lower than those in the reference group and the hemoglobin content was relatively high. After treatment, the improvement of coagulation function in the observation group was better than that in the reference group. The incidence of complications was 21.28% in the reference group and 4.26% in the observation group, the difference was statistically significant (P < 0.05). In the preventive treatment of postpartum hemorrhage, triple medication is more effective, which can improve patients' stress response and serum indexes, reduce the amount of bleeding and improve patients' coagulation function. At the same time, it is also very beneficial to control complications and has high safety.

卡前列素联合催产素、米索前列醇预防产后出血的临床研究。
探讨卡前列素联合催产素、米索前列醇预防产后出血的临床效果。将2022年10月至2023年10月94例产后出血患者分为参照组(应用催产素和米索前列醇治疗)和观察组(应用卡前列素tromethamine、催产素和米索前列醇治疗),分析治疗情况。与对照组比较,观察组患者应激及血清指标均显著降低。除血氧饱和度外,观察组产后出血、止血时间均显著低于对照组,且血红蛋白含量较高。治疗后,观察组凝血功能改善情况优于对照组。对照组并发症发生率为21.28%,观察组为4.26%,差异有统计学意义(P < 0.05)。在产后出血的预防治疗中,三联用药更为有效,可改善患者的应激反应和血清指标,减少出血量,改善患者凝血功能。同时对并发症的控制也非常有利,安全性高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
1.40
自引率
12.50%
发文量
211
审稿时长
4.5 months
期刊介绍: Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013. PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信