[Bronchoscopic Lung Volume Reduction for Severe Emphysema].

Q4 Medicine
Takuma Nakano, Hirotsugu Notsuda, Ken Onodera, Tatsuaki Watanabe, Takashi Hirama, Yoshinori Okada
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引用次数: 0

Abstract

Bronchoscopic lung volume reduction (BLVR) using endobronchial valves is a minimally invasive treatment for severe emphysema. Although lung volume reduction surgery( LVRS) has been employed in selected patients, its high complication rate and limited functional improvement have led to a shift toward non-surgical options. In September 2024, we performed our first BLVR procedure in a transplant candidate who met all eligibility criteria. The patient showed improvement in symptoms and pulmonary function. However, case recruitment remains challenging due to the strict inclusion criteria and limited awareness of BLVR. We report our initial clinical experience, highlight issues in patient selection and recruitment, and discuss the potential of BLVR as a bridging therapy for lung transplantation. In addition, we emphasize its possible utility in elderly or inoperable patients with advanced chronic obstructive pulmonary disease (COPD). Broader dissemination and revision of current eligibility criteria may facilitate wider adoption of this promising therapy.

[支气管镜下肺减容治疗严重肺气肿]。
支气管镜下肺减容术(BLVR)是一种微创治疗严重肺气肿的方法。虽然肺减容手术(LVRS)已被用于部分患者,但其高并发症率和有限的功能改善已导致转向非手术选择。在2024年9月,我们对一位符合所有资格标准的移植候选人进行了第一次BLVR手术。患者症状及肺功能均有改善。然而,由于严格的纳入标准和对BLVR的认识有限,病例招募仍然具有挑战性。我们报告了我们的初步临床经验,强调了患者选择和招募中的问题,并讨论了BLVR作为肺移植桥接治疗的潜力。此外,我们强调其在老年或晚期慢性阻塞性肺疾病(COPD)不能手术患者中的可能应用。更广泛的传播和修订当前的资格标准可能有助于更广泛地采用这种有希望的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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