Clinical outcome assessment may be a more useful tool for supporting inflammatory bowel disease clinical practice than just patient-reported outcome measures.

IF 2.2 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Current Medical Research and Opinion Pub Date : 2025-06-01 Epub Date: 2025-07-23 DOI:10.1080/03007995.2025.2536610
Nagesh Kamat, Gaurav Patil, Ankit Dalal, Amit Maydeo
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引用次数: 0

Abstract

Patients with Inflammatory Bowel Disease approach their treating specialists with a multitude of symptoms. The responses from patient-reported outcome measures (PROM) are challenging to assess and generalize. Most patients who have active disease are happy to discuss their health concerns and get them resolved. Some are wary of the consequences, such as the need for additional investigations, getting hospitalized, intensification of drug therapy or the need for more frequent follow-up. If research surveys or PROM are returned, patients will likely hide sensitive details. They may not reveal the truth, and even though most research surveys are anonymous, the details could be biased. Many patients underreport embarrassing behaviours and thoughts in interviews. Some patient's tendency to deceive remains strong, as there is no motivation to be truthful. Patients often second-guess what the clinician wants to know and then change their answers (socially desirable responding) depending on the survey setting, which can impact study findings. PROM might not be sufficient on their own as reliable measures to reflect disease activity or severity. Research surveys can result in significant misreporting on sensitive topics. The need of the hour is to have flexible endpoints, which can be achieved by appropriate use of clinical outcome assessment wherein treating clinicians' objective observations and assessment are considered.

临床结果评估可能是支持炎症性肠病临床实践的更有用的工具,而不仅仅是患者报告的结果测量。
患有炎症性肠病的患者带着多种症状向他们的治疗专家求助。从患者报告的结果测量(PROM)的反应是具有挑战性的评估和推广。大多数患有活动性疾病的患者都乐于讨论他们的健康问题并解决这些问题。有些人担心后果,如需要额外的调查,住院,加强药物治疗或需要更频繁的随访。如果退回研究调查或PROM,患者可能会隐藏敏感细节。它们可能不会揭示真相,尽管大多数研究调查都是匿名的,但细节可能存在偏见。许多患者在访谈中少报尴尬的行为和想法。有些病人的欺骗倾向仍然很强,因为他们没有诚实的动机。患者经常猜测临床医生想要知道什么,然后根据调查设置改变他们的答案(社会期望的回应),这可能会影响研究结果。PROM本身可能不足以作为反映疾病活动或严重程度的可靠措施。研究调查可能导致对敏感话题的重大误报。时间的需要是有灵活的终点,这可以通过适当使用临床结果评估来实现,其中治疗临床医生的客观观察和评估被考虑在内。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current Medical Research and Opinion
Current Medical Research and Opinion 医学-医学:内科
CiteScore
4.40
自引率
4.30%
发文量
247
审稿时长
3-8 weeks
期刊介绍: Current Medical Research and Opinion is a MEDLINE-indexed, peer-reviewed, international journal for the rapid publication of original research on new and existing drugs and therapies, Phase II-IV studies, and post-marketing investigations. Equivalence, safety and efficacy/effectiveness studies are especially encouraged. Preclinical, Phase I, pharmacoeconomic, outcomes and quality of life studies may also be considered if there is clear clinical relevance
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