Reconfigurable hardware-accelerated, multi-channel, adaptive temperature control platform of VCSELs for high-density fNIRS/DOT.

IF 3.2 2区 医学 Q2 BIOCHEMICAL RESEARCH METHODS
Biomedical optics express Pub Date : 2025-06-03 eCollection Date: 2025-07-01 DOI:10.1364/BOE.562181
Qiao He, Yunjia Xia, Xuhao Zhang, Xinkai Zhou, Yu Liu, Yixuan Huang, Xiangyu Zhou, Aobo Ren, Hubin Zhao, Jiang Wu
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引用次数: 0

Abstract

Functional near-infrared spectroscopy (fNIRS) and its advanced offshoot - diffuse optical tomography (DOT) are promising non-invasive neuroimaging techniques. The advancement of next-generation high-density fNIRS/DOT systems, particularly high-density wearable systems, requires compact light source arrays with high wavelength tuning precision and fine modulation capabilities. Vertical-cavity surface-emitting lasers (VCSELs) have emerged as a strong candidate for this purpose. However, VCSELs' performance is highly sensitive to temperature variations, where heating effects induce wavelength shifts and output power fluctuations, leading to measurement drift and reduced accuracy in fNIRS/DOT data. Conventional multi-channel VCSEL temperature control methods face constraints due to limited computational resources and poor scalability. To address these limitations, we propose a reconfigurable hardware-accelerated temperature control platform based on the heterogeneous ZYNQ-7000 Field-programmable Gate Array (FPGA). By integrating a real-time proportional-integral-derivative (PID) algorithm into the programmable logic (PL), the platform achieves precise temperature regulation with an error margin of ±0.01 °C. Experimental validation demonstrates the encouraging capability of this proposed platform to regulate the temperature of over 100 VCSELs simultaneously while maintaining low resource utilization, ensuring efficient parallel control with large channel counts in real-time. The proposed reconfigurable architecture significantly enhances the reliability and scalability of VCSEL-driven fNIRS/DOT systems while maintaining sufficient resources for future implementations of extra functions. This platform not only improves the thermal stability of VCSELs-based wearable high-density fNIRS/DOT devices but also establishes a robust thermal-control framework for broader applications requiring high-density, thermally stable light source configurations.

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用于高密度fNIRS/DOT的可重构硬件加速、多通道、自适应vcsel温度控制平台。
功能近红外光谱(fNIRS)及其分支漫射光学断层成像技术(DOT)是一种很有前途的无创神经成像技术。下一代高密度fNIRS/DOT系统的发展,特别是高密度可穿戴系统,需要具有高波长调谐精度和精细调制能力的紧凑光源阵列。垂直腔面发射激光器(VCSELs)已成为这一目的的有力候选。然而,VCSELs的性能对温度变化非常敏感,其中加热效应会引起波长偏移和输出功率波动,导致fNIRS/DOT数据的测量漂移和精度降低。传统的多通道VCSEL温度控制方法由于计算资源有限和可扩展性差而受到限制。为了解决这些限制,我们提出了一个基于异构ZYNQ-7000现场可编程门阵列(FPGA)的可重构硬件加速温度控制平台。通过将实时比例-积分-导数(PID)算法集成到可编程逻辑(PL)中,该平台实现了精确的温度调节,误差范围为±0.01℃。实验验证表明,该平台可以同时调节100多个vcsel的温度,同时保持较低的资源利用率,确保实时有效地并行控制大通道数。提出的可重构体系结构显著提高了vcsel驱动的fNIRS/DOT系统的可靠性和可扩展性,同时为未来实现额外功能保留了足够的资源。该平台不仅提高了基于vcsel的可穿戴高密度fNIRS/DOT器件的热稳定性,还为需要高密度、热稳定光源配置的更广泛应用建立了强大的热控制框架。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomedical optics express
Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS
CiteScore
6.80
自引率
11.80%
发文量
633
审稿时长
1 months
期刊介绍: The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.
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