Moslem Kord, Jalil Fath-Abadi, Shahriar Gharibzadeh, Reza Khosrowabadi
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引用次数: 0
Abstract
Introduction: Transcranial electrical stimulation (tES), including transcranial direct current stimulation (tDCS) and transcranial random noise stimulation (tRNS), can improve neuropsychological and cognitive deficits in attention deficit hyperactivity disorder (ADHD). Here, we investigated the effectiveness of various tES modes combined with working memory training in children and adolescents with ADHD.
Methods: Participants in this study consisted of a cohort of 13- to 17-year-old adolescents (N=45) who were diagnosed with ADHD in 2018. They were randomly assigned to three groups: tDCS, tRNS, and the active control (sham). The three groups received five sessions of tES either as an intervention or sham on the left and right prefrontal areas (F3 and F4). In addition to tES, dual n-back training was used in the three groups. The Wechsler's digit span subtest and resting state electroencephalography (EEG) data were collected before and after brain stimulation.
Results: Analysis of variance showed significant differences between the groups in some EEG channels (P=0.05). The absolute power analysis of the brain waves data in the pre-test and post-test phases reveals that the tDCS group has the greatest changes compared to the other two groups and that most changes in the absolute power related to theta, delta, and alpha bands were found in the frontal and occipital regions.
Conclusion: Based on the results, we concluded that tES over the prefrontal area induced cortical changes in children and adolescents with ADHD. Thus, it seems that various methods of tES can be used in combination with other common types of intervention to treat ADHD.
期刊介绍：
BCN is an international multidisciplinary journal that publishes editorials, original full-length research articles, short communications, reviews, methodological papers, commentaries, perspectives and “news and reports” in the broad fields of developmental, molecular, cellular, system, computational, behavioral, cognitive, and clinical neuroscience. No area in the neural related sciences is excluded from consideration, although priority is given to studies that provide applied insights into the functioning of the nervous system. BCN aims to advance our understanding of organization and function of the nervous system in health and disease, thereby improving the diagnosis and treatment of neural-related disorders. Manuscripts submitted to BCN should describe novel results generated by experiments that were guided by clearly defined aims or hypotheses. BCN aims to provide serious ties in interdisciplinary communication, accessibility to a broad readership inside Iran and the region and also in all other international academic sites, effective peer review process, and independence from all possible non-scientific interests. BCN also tries to empower national, regional and international collaborative networks in the field of neuroscience in Iran, Middle East, Central Asia and North Africa and to be the voice of the Iranian and regional neuroscience community in the world of neuroscientists. In this way, the journal encourages submission of editorials, review papers, commentaries, methodological notes and perspectives that address this scope.
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