Impacts of 60Co-γ irradiation on physicochemical characteristics and antioxidant activity of Tibetan medicine Pazhu powder (PP)

IF 2.6 3区工程技术 Q1 NUCLEAR SCIENCE & TECHNOLOGY

Nuclear Engineering and Technology Pub Date : 2025-07-18 DOI:10.1016/j.net.2025.103584

Yue Yang , Le Zhong , Rang yan po Luo , Zhong si ji Yang , Weishan Qiu , Juhong An , Rui Gu , Shihong Zhong

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引用次数: 0

Abstract

In order to explore the effect of ⁶⁰Co-γ irradiation on the quality of Tibetan medicine preparations, this study selected Pazhu powder (PP) which has complex and diverse components for research. PP was irradiated at doses of 3, 6, 10, 15, 20, 50, and 100 kGy of ⁶⁰Co-γ, Then the effects on color, odor, structural characterization, chemical composition and antioxidant activity were investigated. Results showed that after irradiation, the color, the content of aldehydes and ketones in volatile components were not changed. While the structure and the HPLC fingerprints changed slightly. However, the contents of terpenes, alkanes, amides and alcohols in the volatile components, and all the non-volatile components showed a dose-related decline in irradiated samples. Furthermore, the antioxidant activity increased after irradiation. These findings suggest that ⁶⁰Co-γ irradiation has a great influence on the chemical composition of PP. It's necessary to cautiously set reasonable irradiation dose for Tibetan medicine preparations.

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60Co-γ辐照对藏药巴珠粉理化特性及抗氧化活性的影响

为探讨60Co-γ辐照对藏药制剂质量的影响，本研究选取成分复杂多样的巴珠粉进行研究。以60Co-γ浓度为3、6、10、15、20、50和100 kGy的剂量辐照PP，考察其颜色、气味、结构表征、化学成分和抗氧化活性的变化。结果表明，辐照后，其颜色、挥发性成分中醛类和酮类的含量均无明显变化。而结构和HPLC指纹图谱变化不大。然而，在辐照样品中，挥发性组分和所有非挥发性组分中的萜烯、烷烃、酰胺和醇的含量呈剂量相关性下降。此外，辐照后抗氧化活性增强。说明60Co-γ辐照对PP的化学成分有较大影响，藏药制剂应谨慎设置合理的辐照剂量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nuclear Engineering and Technology 工程技术-核科学技术

CiteScore

4.80

自引率

7.40%

发文量

431

审稿时长

3.5 months

期刊介绍： Nuclear Engineering and Technology (NET), an international journal of the Korean Nuclear Society (KNS), publishes peer-reviewed papers on original research, ideas and developments in all areas of the field of nuclear science and technology. NET bimonthly publishes original articles, reviews, and technical notes. The journal is listed in the Science Citation Index Expanded (SCIE) of Thomson Reuters. NET covers all fields for peaceful utilization of nuclear energy and radiation as follows: 1) Reactor Physics 2) Thermal Hydraulics 3) Nuclear Safety 4) Nuclear I&C 5) Nuclear Physics, Fusion, and Laser Technology 6) Nuclear Fuel Cycle and Radioactive Waste Management 7) Nuclear Fuel and Reactor Materials 8) Radiation Application 9) Radiation Protection 10) Nuclear Structural Analysis and Plant Management & Maintenance 11) Nuclear Policy, Economics, and Human Resource Development