Associations of BMI, sleep quality, and sleep duration trajectories with new-onset diabetes mellitus in the elderly

IF 4.2 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

Obesity Pub Date : 2025-07-16 DOI:10.1002/oby.24338

Shanshan Li, Boyi Yang, Shasha Shang, Wei Jiang

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引用次数: 0

Abstract

Objective

Our objective was to investigate the relationships between BMI, sleep quality, and sleep duration trajectories and new-onset diabetes mellitus (NODM) in the elderly.

Methods

We analyzed 2648 diabetes-free participants aged ≥60 years from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) in 2014. Using Cox proportional hazards models, we examined the associations of BMI, self-reported sleep quality, and sleep duration trajectories (categorized as persistent short, persistent normal, persistent long, low-increasing, normal-decreasing, normal-increasing, and long-decreasing) with NODM risk over 4 years. Diabetes diagnosis was self-reported.

Results

Over 4 years, 94 participants developed NODM. Obesity was associated with the highest risk (adjusted hazard ratio [HR] 2.247 [CI: 1.212–4.168]). Compared with individuals with good sleep quality, those with poor sleep quality showed an increased risk of NODM, but this association was not statistically significant (HR 1.570 [0.903–2.731]). Additionally, persistent short, normal-decreasing, and long-decreasing sleep trajectories were associated with elevated NODM risk (adjusted HR values 11.662 [CI: 1.565–86.896], 8.403 [CI: 1.023–69.010], and 9.474 [CI: 1.269–70.700]).

Conclusions

BMI, sleep quality, and sleep duration trajectories are associated with NODM risk. Individuals with higher BMI values, poor sleep quality, or persistent short or decreasing sleep duration may be at higher risk for NODM, warranting further attention.

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体重指数、睡眠质量和睡眠时间轨迹与老年人新发糖尿病的关系

目的：探讨老年人BMI、睡眠质量和睡眠时间轨迹与新发糖尿病（NODM）的关系。方法：我们分析了2014年中国纵向健康寿命调查（CLHLS）中2648名年龄≥60岁的无糖尿病参与者。使用Cox比例风险模型，我们检查了4年内BMI、自我报告的睡眠质量和睡眠持续时间轨迹（分类为持续短、持续正常、持续长、低增加、正常减少、正常增加和长减少）与NODM风险的关系。糖尿病诊断是自我报告。结果：在4年多的时间里，94名参与者发展为NODM。肥胖与最高风险相关（校正风险比[HR] 2.247 [CI: 1.212-4.168]）。与睡眠质量好的个体相比，睡眠质量差的个体发生NODM的风险增加，但这种相关性无统计学意义（HR 1.570[0.903-2.731]）。此外，持续的短、正常下降和长时间下降的睡眠轨迹与NODM风险升高相关（调整后的HR值为11.662 [CI: 1.565-86.896]、8.403 [CI: 1.023-69.010]和9.474 [CI: 1.69 -70.700]）。结论：BMI、睡眠质量和睡眠持续时间轨迹与NODM风险相关。BMI值较高、睡眠质量差或持续睡眠时间短或减少的个体可能具有更高的NODM风险，值得进一步关注。

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来源期刊

Obesity 医学-内分泌学与代谢

CiteScore

11.70

自引率

1.40%

发文量

261

审稿时长

2-4 weeks

期刊介绍： Obesity is the official journal of The Obesity Society and is the premier source of information for increasing knowledge, fostering translational research from basic to population science, and promoting better treatment for people with obesity. Obesity publishes important peer-reviewed research and cutting-edge reviews, commentaries, and public health and medical developments.