Visual Outcomes and Complication Rates of Cataract Surgery in Asian High Myopic Patients: A Meta-Analysis and Systematic Review.

Clinical ophthalmology (Auckland, N.Z.) Pub Date : 2025-07-12 eCollection Date: 2025-01-01 DOI:10.2147/OPTH.S532853
Ke-Bing Zhao, Jing-Shang Zhang, Xiu-Hua Wan
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Abstract

Purpose: To evaluate the visual outcomes and complication rates of cataract surgery in high myopic patients through a systematic review and meta-analysis.

Methods: Following the PRISMA 2020 guidelines, a comprehensive literature search was conducted across multiple databases to identify studies reporting on cataract surgery outcomes in highly myopic patients. Eight studies, involving 1,996 patients (2,826 eyes), were included in the meta-analysis. Data on pre- and postoperative best-corrected visual acuity (BCVA), intraoperative and postoperative complications, and study characteristics were extracted. Random-effects models were used to calculate pooled estimates due to significant heterogeneity among studies.

Results: Cataract surgery significantly improved BCVA in high myopic patients, with an average improvement of -1.72 logMAR units (95% CI: -2.37 to -1.06). Substantial heterogeneity was observed across studies (I² = 84.4%, 95% CI: 65.2%-93.1%). Intraoperative and postoperative complications occurred at the following pooled incidences: transient intraocular pressure (IOP) elevation 13.03% (95% CI, 9.59%-17.47%), posterior capsule opacification (PCO) at 12.11% (95% CI, 4.00%-31.30%), cystoid macular edema (CME) at 2.41% (95% CI, 0.84%-6.76%), intraoperative posterior capsule rupture (PCR) at 2.01% (95% CI, 0.89%-4.44%), retinal detachment (RD) at 1.97% (95% CI, 1.21%-3.21%), retinal breaks at 1.89% (95% CI, 0.85%-4.14%) and intraocular lens (IOL) dislocation at 0.67% (95% CI, 0.21%-2.04%).

Conclusion: Cataract surgery is effective in improving vision in highly myopic patients but is associated with a moderate risk of complications. The high heterogeneity among studies underscores the need for standardized methodologies and more comprehensive assessments of ocular health in future research. These findings provide valuable insights for optimizing clinical management and enhancing patient counseling.

亚洲高度近视患者白内障手术的视力结果和并发症发生率:荟萃分析和系统评价。
目的:通过系统回顾和荟萃分析,评价高度近视患者白内障手术的视力结局和并发症发生率。方法:根据PRISMA 2020指南,在多个数据库中进行全面的文献检索,以确定报道高度近视患者白内障手术结果的研究。meta分析纳入了8项研究,涉及1996名患者(2826只眼睛)。提取术前和术后最佳矫正视力(BCVA)、术中和术后并发症以及研究特征的数据。由于研究之间存在显著的异质性,我们使用随机效应模型来计算汇总估计。结果:白内障手术可显著改善高度近视患者的BCVA,平均改善-1.72 logMAR单位(95% CI: -2.37 ~ -1.06)。研究间观察到大量异质性(I²= 84.4%,95% CI: 65.2%-93.1%)。术中及术后并发症发生率如下:一过性眼压升高13.03% (95% CI, 9.59%-17.47%),后囊混浊(PCO) 12.11% (95% CI, 4.00%-31.30%),囊样黄斑水肿(CME) 2.41% (95% CI, 0.84%-6.76%),术中后囊破裂(PCR) 2.01% (95% CI, 0.89%-4.44%),视网膜脱离(RD) 1.97% (95% CI, 1.21%-3.21%),视网膜破裂1.89% (95% CI, 0.85%-4.14%),人工晶状体(IOL)脱位0.67% (95% CI, 0.21%-2.04%)。结论:白内障手术可有效改善高度近视患者的视力,但存在中度并发症风险。研究之间的高度异质性强调了在未来的研究中需要标准化的方法和更全面的眼健康评估。这些发现为优化临床管理和加强患者咨询提供了有价值的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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