{"title":"Effects of skipping breakfast, lunch or dinner on subsequent postprandial blood glucose levels among healthy young adults.","authors":"Chisato Kanazawa, Yuki Shimba, Saki Toyonaga, Fuzuki Nakamura, Toshio Hosaka","doi":"10.1186/s12986-025-00975-4","DOIUrl":null,"url":null,"abstract":"<p><p>Meal skipping has become increasingly common in modern society due to changes in lifestyle. While the adverse effects of skipping breakfast on postprandial glucose levels have been well established, less is known about the impact of skipping lunch or dinner on these levels. The aim of this study is to determine the effect of skipping breakfast, lunch, and dinner consecutively on postprandial glucose levels in healthy subjects. Thirteen healthy young adults were enrolled and instructed to consume meals freely at designated times while maintaining detailed food intake records. Participants then followed a controlled protocol in which one of the three meals was skipped for two consecutive days in a specified order, with interstitial glucose continuously monitored. Skipping lunch on both days significantly increased postprandial glucose levels at the subsequent dinner by 1.6 mmol/L compared to when lunch was consumed and breakfast was skipped (p < 0.001). In contrast, skipping dinner or breakfast did not result in significant changes in postprandial glucose levels at the following meal. We thus observed skipping each of these three meals to have different effects on subsequent postprandial blood glucose levels in the healthy subjects. Most notably, skipping lunch leads to increased postprandial blood glucose levels at dinner.</p>","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":"22 1","pages":"76"},"PeriodicalIF":3.9000,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12265207/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrition & Metabolism","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12986-025-00975-4","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0
Abstract
Meal skipping has become increasingly common in modern society due to changes in lifestyle. While the adverse effects of skipping breakfast on postprandial glucose levels have been well established, less is known about the impact of skipping lunch or dinner on these levels. The aim of this study is to determine the effect of skipping breakfast, lunch, and dinner consecutively on postprandial glucose levels in healthy subjects. Thirteen healthy young adults were enrolled and instructed to consume meals freely at designated times while maintaining detailed food intake records. Participants then followed a controlled protocol in which one of the three meals was skipped for two consecutive days in a specified order, with interstitial glucose continuously monitored. Skipping lunch on both days significantly increased postprandial glucose levels at the subsequent dinner by 1.6 mmol/L compared to when lunch was consumed and breakfast was skipped (p < 0.001). In contrast, skipping dinner or breakfast did not result in significant changes in postprandial glucose levels at the following meal. We thus observed skipping each of these three meals to have different effects on subsequent postprandial blood glucose levels in the healthy subjects. Most notably, skipping lunch leads to increased postprandial blood glucose levels at dinner.
期刊介绍:
Nutrition & Metabolism publishes studies with a clear focus on nutrition and metabolism with applications ranging from nutrition needs, exercise physiology, clinical and population studies, as well as the underlying mechanisms in these aspects.
The areas of interest for Nutrition & Metabolism encompass studies in molecular nutrition in the context of obesity, diabetes, lipedemias, metabolic syndrome and exercise physiology. Manuscripts related to molecular, cellular and human metabolism, nutrient sensing and nutrient–gene interactions are also in interest, as are submissions that have employed new and innovative strategies like metabolomics/lipidomics or other omic-based biomarkers to predict nutritional status and metabolic diseases.
Key areas we wish to encourage submissions from include:
-how diet and specific nutrients interact with genes, proteins or metabolites to influence metabolic phenotypes and disease outcomes;
-the role of epigenetic factors and the microbiome in the pathogenesis of metabolic diseases and their influence on metabolic responses to diet and food components;
-how diet and other environmental factors affect epigenetics and microbiota; the extent to which genetic and nongenetic factors modify personal metabolic responses to diet and food compositions and the mechanisms involved;
-how specific biologic networks and nutrient sensing mechanisms attribute to metabolic variability.