Methodology of the Updated and Expanded Australasian Bronchiolitis Guideline

IF 1.4 4区医学 Q2 PEDIATRICS

Journal of paediatrics and child health Pub Date : 2025-07-17 DOI:10.1111/jpc.70145

Kate Loveys, Emma J. Tavender, Franz E. Babl, Elizabeth Cotterell, Libby Haskell, Sharon O’Brien, Ed Oakley, Catherine Wilson, Meredith L. Borland, Stuart R. Dalziel, the Paediatric Research in Emergency Departments International Collaborative (PREDICT) Network

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引用次数: 0

Abstract

Background

Bronchiolitis is the most common reason for hospital admission in infants in Australia and Aotearoa New Zealand (AoNZ), with care historically affected by practice variation, including use of ineffective therapies. The Paediatric Research in Emergency Departments International Collaborative (PREDICT) developed the first Australasian (Australia, AoNZ) bronchiolitis guideline in 2016, providing evidence-based guidance on the management of infants (< 12 months of age), presenting or admitted to hospital with bronchiolitis. In 2022, PREDICT initiated a guideline update to include new evidence and expand the scope to include intensive care (up to intubation), management of SARS-CoV-2 co-infection, and respiratory syncytial virus prevention.

Aim

This article outlines the methodology used in the guideline update, following AGREE and CheckUp reporting standards.

Methods

A Guideline Advisory Group and Guideline Development Committee, consisting of 29 clinical and methodological experts from Australasia, developed the guideline with consumer input. Forty-one scoping questions on 25 topics were investigated. Systematic searches were performed by a subject librarian across five electronic databases (last search 24/01/24). Screening of 13,932 new articles occurred independently, in duplicate in two stages. The results of 431 articles were synthesized narratively and quantitatively where appropriate, per topic. Risk of bias was evaluated using appropriate tools. GRADE methodology was used to assess evidence quality and develop the recommendations, which were finalised through consensus voting across three guideline development meetings.

Results

The update produced 41 recommendations (33 evidence-based, 8 consensus-based; including 11 new and 7 with key revisions), covering bronchiolitis investigations, management and RSV prevention. Interest-holder groups consulted on the recommendations.

Conclusion

The Australasian Bronchiolitis Guideline was updated and expanded according to AGREE and CheckUp reporting standards.

查看原文本刊更多论文

更新和扩展的澳大利亚细支气管炎指南的方法学。

背景：毛细支气管炎是澳大利亚和新西兰（AoNZ）婴儿住院的最常见原因，其护理历史上受到实践变化的影响，包括使用无效的治疗方法。2016年，急诊科儿科研究国际合作组织（PREDICT）制定了第一个澳大利亚（Australia, AoNZ）毛细支气管炎指南，为婴儿的管理提供了循证指导(目的：本文概述了指南更新中使用的方法，遵循了AGREE和CheckUp报告标准。方法：由来自澳大利亚的29名临床和方法学专家组成的指南咨询小组和指南制定委员会根据消费者的意见制定了指南。调查了25个主题的41个范围问题。系统检索由学科馆员在5个电子数据库中完成（最后检索时间为24/01/24）。13932篇新文章的筛选是独立进行的，分两个阶段进行。431篇文章的结果在适当的情况下对每个主题进行了叙述和定量的综合。使用适当的工具评估偏倚风险。GRADE方法用于评估证据质量并制定建议，这些建议通过三次指南制定会议的共识投票最终确定。结果：更新产生了41项建议(33项基于证据，8项基于共识；包括11个新版本和7个关键修订版本)，涵盖细支气管炎调查、管理和RSV预防。利益相关者团体就这些建议进行了咨询。结论：澳大利亚细支气管炎指南根据AGREE和CheckUp报告标准进行了更新和扩展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of paediatrics and child health 医学-小儿科

CiteScore

2.90

自引率

5.90%

发文量

487

审稿时长

3-6 weeks

期刊介绍： The Journal of Paediatrics and Child Health publishes original research articles of scientific excellence in paediatrics and child health. Research Articles, Case Reports and Letters to the Editor are published, together with invited Reviews, Annotations, Editorial Comments and manuscripts of educational interest.