Rosita Sortino, Sophie M Eschlboeck, Christoph Kuemmerli, Martin Bolli
{"title":"Barbed Suture for Pancreaticojejunal Anastomosis: An Ally Against Pancreatic Fistula.","authors":"Rosita Sortino, Sophie M Eschlboeck, Christoph Kuemmerli, Martin Bolli","doi":"10.1002/jso.70048","DOIUrl":null,"url":null,"abstract":"<p><p>Pancreaticoduodenectomy (PD) is the standard treatment for resectable pancreatic head disease. The pancreatic anastomosis constitutes the mainstay of this procedure and is one of the drivers of its morbidity. Despite the development of a variety of techniques for pancreaticojejunostomy or pancreaticogastrostomy, high rates of postoperative pancreatic fistula (POPF), hampering early and fast patient recovery, are still reported. Here, based on the analysis of a cohort of 16 patients operated over 2 years, we describe a pancreaticojejunal anastomosis technique taking advantage of unidirectional barbed sutures. Although six of these patients were classified as \"high risk,\" according to updated International Study Group of Pancreatic Fistula (ISGPS) recommendations, we only observed one grade B POPF requiring antibiotic treatment, prolonged fasting and parenteral nutrition during the postoperative course. While larger studies are necessary to clarify this issue, our data suggests that barbed sutures could help prevent POPF development following PD.</p>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Surgical Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/jso.70048","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Pancreaticoduodenectomy (PD) is the standard treatment for resectable pancreatic head disease. The pancreatic anastomosis constitutes the mainstay of this procedure and is one of the drivers of its morbidity. Despite the development of a variety of techniques for pancreaticojejunostomy or pancreaticogastrostomy, high rates of postoperative pancreatic fistula (POPF), hampering early and fast patient recovery, are still reported. Here, based on the analysis of a cohort of 16 patients operated over 2 years, we describe a pancreaticojejunal anastomosis technique taking advantage of unidirectional barbed sutures. Although six of these patients were classified as "high risk," according to updated International Study Group of Pancreatic Fistula (ISGPS) recommendations, we only observed one grade B POPF requiring antibiotic treatment, prolonged fasting and parenteral nutrition during the postoperative course. While larger studies are necessary to clarify this issue, our data suggests that barbed sutures could help prevent POPF development following PD.
期刊介绍:
The Journal of Surgical Oncology offers peer-reviewed, original papers in the field of surgical oncology and broadly related surgical sciences, including reports on experimental and laboratory studies. As an international journal, the editors encourage participation from leading surgeons around the world. The JSO is the representative journal for the World Federation of Surgical Oncology Societies. Publishing 16 issues in 2 volumes each year, the journal accepts Research Articles, in-depth Reviews of timely interest, Letters to the Editor, and invited Editorials. Guest Editors from the JSO Editorial Board oversee multiple special Seminars issues each year. These Seminars include multifaceted Reviews on a particular topic or current issue in surgical oncology, which are invited from experts in the field.