Tao Zeng, Zi-Liang Chen, Yao-Hui Zhou, Wei-Qi Liu, Jian Chen, Jian-Hui Lu, Jia-Hao Lin
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引用次数: 0
Abstract
Introduction: Acute gastric dilatation (AGD) is a rare but clinically significant condition characterized by abnormal enlargement of the stomach. It can lead to serious complications such as gastric necrosis, perforation, and respiratory failure if not promptly managed. AGD has been associated with mechanical obstructions, binge eating, and systemic conditions like diabetes mellitus. However, AGD induced by excessive consumption of traditional Chinese medicine (TCM) has not been previously reported.
Patient concerns: A 40-year-old male with a history of chronic dyspepsia presented to the emergency department with recurrent vomiting. Over the 3 days prior to admission, he self-reported consuming approximately 3.5 liters of TCM liquid (about 1.1-1.3 liters per day). This attempt to alleviate his chronic dyspepsia symptoms failed to show the expected therapeutic effect. The patient denied experiencing headache, dizziness, chest pain, palpitations, abdominal pain, or diarrhea.
Diagnosis: Abdominal CT revealed significant gastric distension, and subsequent endoscopy showed pyloric ulcer with stenosis, gastric retention, chronic atrophic gastritis, and a relaxed cardia. Laboratory investigations indicated metabolic alkalosis, electrolyte imbalances, and signs of tissue hypoxia.
Interventions: The patient was immediately managed with nasogastric tube decompression, anti-infection therapy, gastric mucosal protection, fluid resuscitation, parenteral nutritional support, fasting, and gastrointestinal decompression.
Outcomes: The patient's symptoms and signs notably improved after these interventions. A follow-up CT scan demonstrated improved gastric dilation. At a 4-week follow-up, the patient reported complete resolution of vomiting and resumed normal oral intake. Repeat endoscopy showed healed pyloric ulcers and improved gastric motility. No adverse events (e.g., rehospitalization or medication intolerance) were reported during a 3-month follow-up period.
Conclusion: This case highlights the necessity of including AGD in the differential diagnosis for patients presenting with frequent vomiting after excessive consumption of TCM. It underscores the importance of thorough evaluation to prevent misdiagnosis and severe complications. The case also emphasizes the need for caution when using TCM, especially in patients with organic lesions or pyloric obstruction.
期刊介绍:
Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
In addition to papers that provide a link between basic research and clinical practice, a particular emphasis is given to studies that are directly relevant to patient care. In this spirit, the journal publishes the latest research results and medical knowledge that facilitate the translation of scientific advances into new therapies or diagnostic tools. The full listing of the Specialty Sections represented by Frontiers in Medicine is as listed below. As well as the established medical disciplines, Frontiers in Medicine is launching new sections that together will facilitate
- the use of patient-reported outcomes under real world conditions
- the exploitation of big data and the use of novel information and communication tools in the assessment of new medicines
- the scientific bases for guidelines and decisions from regulatory authorities
- access to medicinal products and medical devices worldwide
- addressing the grand health challenges around the world