On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death.

IF 96.2 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL
John A Kucera,Douglas M Overbey,Joseph W Turek
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引用次数: 0

Abstract

Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list times and resultant deaths in this population. Donation after circulatory death (DCD) with normothermic regional perfusion has the potential to increase the donor pool by up to 30%. Ethical concerns have limited adoption of this technique in the United States and abroad. Consequently, a method facilitating ex vivo resuscitation of hearts from deceased donors after circulatory death (i.e., DCD hearts) is needed. We describe an on-table reanimation of a pediatric DCD heart transplanted into a 3-month-old recipient. Adverse events are reported.
循环性死亡后捐赠儿童心脏的手术台上复活
心脏同种异体移植在患有终末期心力衰竭或不可修复的先天性心脏病的儿童中是有保证的。器官移植的缺乏导致了这一人群等待移植的时间过长,从而导致死亡。循环性死亡(DCD)后的捐献加上常温区域灌注有可能使供体池增加30%。伦理问题限制了这项技术在美国和国外的应用。因此,需要一种促进循环死亡后已故供体心脏体外复苏的方法(即DCD心脏)。我们描述了一个儿科DCD心脏移植到一个3个月大的接受者的表上复活。不良事件有报道。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
New England Journal of Medicine
New England Journal of Medicine 医学-医学:内科
CiteScore
145.40
自引率
0.60%
发文量
1839
审稿时长
1 months
期刊介绍: The New England Journal of Medicine (NEJM) stands as the foremost medical journal and website worldwide. With an impressive history spanning over two centuries, NEJM boasts a consistent publication of superb, peer-reviewed research and engaging clinical content. Our primary objective revolves around delivering high-caliber information and findings at the juncture of biomedical science and clinical practice. We strive to present this knowledge in formats that are not only comprehensible but also hold practical value, effectively influencing healthcare practices and ultimately enhancing patient outcomes.
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