[Nonbacterial osteitis: innovations in imaging : Advances in radiology and clinical management].

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Radiologie (Heidelberg, Germany) Pub Date : 2025-09-01 Epub Date: 2025-07-16 DOI:10.1007/s00117-025-01479-1

Haroun Bel Hadj Jrad, Markus Hufnagel

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Abstract

Background: Nonbacterial osteitis (NBO) is a rare autoinflammatory bone disease primarily affecting children and adolescents. The absence of a unified definition and standardized diagnostic criteria complicates clinical diagnosis and management.

Objectives: This study aims to systematically review the current literature regarding the definition of NBO and assess the role of imaging particularly whole-body magnetic resonance imaging (MRI) as well as the use of the radiologic index for nonbacterial osteitis (RINBO) score in diagnosis and disease monitoring.

Materials and methods: A thorough literature review was conducted, focusing on radiological methods including whole-body magnetic resonance imaging (WB MRI) and the application of the RINBO score.

Results: Whole-body MRI demonstrates high sensitivity for detecting inflammatory bone lesions and proves useful for both diagnosis and follow-up. Conventional X‑ray imaging offers additional information about structural bone damage. The RINBO score serves as a practical tool for standardizing diagnostic interpretation.

Conclusion: The combination of whole-bodyMRI and the RINBO score enables structured and reproducible evaluation of NBO. Establishing uniform diagnostic criteria remains a central goal for future research.

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[非细菌性骨炎：影像学创新：放射学和临床管理进展]。

背景：非细菌性骨炎（NBO）是一种罕见的自身炎症性骨病，主要影响儿童和青少年。缺乏统一的定义和标准化的诊断标准，使临床诊断和管理复杂化。目的：本研究旨在系统地回顾目前关于NBO定义的文献，评估影像学尤其是全身磁共振成像（MRI）的作用，以及非细菌性骨炎（RINBO）评分在诊断和疾病监测中的应用。材料和方法：我们进行了全面的文献综述，重点是放射学方法，包括全身磁共振成像（WB MRI）和RINBO评分的应用。结果：全身MRI对炎性骨病变的检测具有较高的敏感性，对诊断和随访均有一定的帮助。传统的X射线成像提供了关于骨结构损伤的额外信息。RINBO评分是标准化诊断解释的实用工具。结论：结合全身mri和RINBO评分可以对NBO进行结构化和可重复的评估。建立统一的诊断标准仍然是未来研究的中心目标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Radiologie (Heidelberg, Germany)

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