Differentiating odontogenic myxoma from ameloblastoma by focusing on cyst-like areas on MR images.

IF 1.6 3区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Radiology Pub Date : 2025-07-16 DOI:10.1007/s11282-025-00841-2

Ami Kuribayashi, Shin Nakamura, Hiroshi Watanabe, Sakurako Kawashima, Shinya Kotaki, Akiko Imaizumi, Hiroshi Tomisato, Yoshikazu Nomura, Miharu Taguchi, Arisa Oki, Sakiko Kume, Masahiko Miura

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引用次数: 0

Abstract

Objectives: This study aimed to identify characteristic findings of odontogenic myxoma (OM) and assess the role of MRI in differentiating OM from ameloblastoma by analysing cyst-like areas.

Methods: MRI images from 12 and 15 patients with OM and ameloblastoma, respectively, were retrospectively evaluated to determine imaging features useful for differentiation. We analysed cyst-like areas in OM using apparent diffusion coefficient (ADC) values and gadolinium contrast patterns, comparing them with those in ameloblastoma. ADC values were statistically assessed via the Mann-Whitney U test.

Results: In OM, the mean ADC value of cyst-like areas was 1.84 × 10⁻³ mm²/s. Contrast-enhanced T1-weighted images showed signal enhancement, with a gradual increase on dynamic contrast-enhanced MRI (DCE-MRI). Conversely, in ameloblastoma, the mean ADC value was 2.28 × 10⁻³ mm²/s. Unlike OM, its cyst-like areas lacked enhancement, with only the solid areas exhibiting a rapid signal increase on DCE-MRI. ADC values were significantly higher in ameloblastoma (P < 0.05).

Conclusions: The presence or absence of contrast enhancement in cyst-like areas aids in differentiating OM from ameloblastoma. Additionally, ADC values may be used to differentiate between these tumors in the absence of contrast agents.

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鉴别牙源性黏液瘤和成釉细胞瘤的MR图像囊肿样区域。

目的：本研究旨在确定牙源性黏液瘤（OM）的特征表现，并通过分析囊肿样区域评估MRI在OM与成釉细胞瘤鉴别中的作用。方法：回顾性分析12例和15例OM和成釉细胞瘤的MRI图像，以确定有助于鉴别的影像学特征。我们使用表观扩散系数（ADC）值和钆对比图分析OM的囊肿样区域，并将其与成釉细胞瘤进行比较。通过Mann-Whitney U检验对ADC值进行统计评估。结果：OM中囊样区ADC平均值为1.84 × 10 - 3 mm2/s。对比增强t1加权图像显示信号增强，动态对比增强MRI （DCE-MRI）逐渐增强。相反，在成釉细胞瘤中，平均ADC值为2.28 × 10⁻3 mm2/s。与OM不同，其囊肿样区域缺乏增强，仅实性区域在DCE-MRI上表现为快速信号增强。结论：囊样区造影增强的存在或不存在有助于OM与成釉细胞瘤的鉴别。此外，在没有造影剂的情况下，ADC值可用于区分这些肿瘤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

4.20

自引率

13.60%

发文量

审稿时长

>12 weeks

期刊介绍： As the official English-language journal of the Japanese Society for Oral and Maxillofacial Radiology and the Asian Academy of Oral and Maxillofacial Radiology, Oral Radiology is intended to be a forum for international collaboration in head and neck diagnostic imaging and all related fields. Oral Radiology features cutting-edge research papers, review articles, case reports, and technical notes from both the clinical and experimental fields. As membership in the Society is not a prerequisite, contributions are welcome from researchers and clinicians worldwide.