Outcomes of N0 Necks in Primary Parotid Carcinoma: A Multi-Institution Study Over Ten Years.

IF 1.5 4区医学 Q2 OTORHINOLARYNGOLOGY

Clinical Otolaryngology Pub Date : 2025-07-15 DOI:10.1111/coa.70000

Harriet Cunniffe, Jeremy Wong, Richard Jackson, Belen Kornfeld, Alfred Addison, Katerina Karamali, Brian Fish, Ramez Nassif

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引用次数: 0

Abstract

Aims: To determine in patients with clinical and radiological N0 necks in primary parotid carcinoma: (1) Rate of occult node positivity post-neck dissection. (2) Outcomes following elective neck dissection ± radiotherapy. (3) Factors predicting recurrence and mortality following treatment.

Methods: A retrospective study on patients diagnosed with malignant neoplasm of the parotid between January 2007 and December 2018 from three UK tertiary centres.

Results: One hundred and thirty-four patients were identified. 6% (4/62) of patients who underwent neck dissection for radiologically N0 neck had positive lymph nodes. There was no statistically significant feature associated with recurrence and disease-related mortality, but recurrence was associated with an increased risk of mortality (HR 1.444).

Conclusion: This study has demonstrated a low rate of occult nodal disease in N0 parotid malignancy and suggests that high-grade disease has a higher risk of nodal disease and recurrence. These patients may benefit from elective neck treatment, but more prospective data is required.

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非颈部原发性腮腺癌的预后：一项超过十年的多机构研究。

目的：探讨原发性腮腺癌患者的临床及影像学表现：(1)颈部清扫术后隐匿淋巴结阳性率。(2)择期颈部清扫±放疗后的结果。(3)预测治疗后复发和死亡的因素。方法：回顾性研究2007年1月至2018年12月英国三家三级中心诊断为腮腺恶性肿瘤的患者。结果：共鉴定出134例患者。6%（4/62）的患者接受了放射学上的N0颈部清扫术，淋巴结呈阳性。复发和疾病相关死亡率无统计学意义，但复发与死亡风险增加相关（HR 1.444）。结论：本研究显示N0腮腺恶性肿瘤隐匿性淋巴结病变发生率低，提示高级别病变发生淋巴结病变和复发的风险较高。这些患者可能受益于择期颈部治疗，但需要更多的前瞻性数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Otolaryngology 医学-耳鼻喉科学

CiteScore

4.00

自引率

4.80%

发文量

106

审稿时长

>12 weeks

期刊介绍： Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with: current otorhinolaryngological practice audiology, otology, balance, rhinology, larynx, voice and paediatric ORL head and neck oncology head and neck plastic and reconstructive surgery continuing medical education and ORL training The emphasis is on high quality new work in the clinical field and on fresh, original research. Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject. • Negative/null results In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.