Toward improving multiomic research in understudied cereals

IF 31.7 1区 生物学 Q1 GENETICS & HEREDITY
Fanjing Yang, Xiaojiao Gong, Pan Zhao, Lingtong Cheng, Yujie Zhang, Yingting Luo, Qian-Hao Zhu, Chu-Yu Ye
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引用次数: 0

Abstract

With the looming challenges of climate change and population pressure, understudied cereals hold notably untapped potential for future global food security and sustainable agriculture due to their unique nutritional profiles and notable stress resilience. Multiomics holds great promise in realizing the value of understudied cereals by understanding the genetic basis and molecular mechanisms regulating their unique traits; however, multiomic studies of understudied cereals still lag behind those of major cereals, hindering their genetic improvement and wide adoption in modern agriculture. Here, we discuss the limitations and challenges in multiomic studies of understudied cereals and how they can be overcome to enhance utilization of the traits unique to understudied cereals in improving both themselves and major cereals. We also offer a database specific to understudied cereals, including multiomics data from 12 understudied cereals and wild relatives for some of these, to serve the community.

Abstract Image

改进未充分研究谷物的多组学研究
随着气候变化和人口压力的挑战迫在眉睫,未得到充分研究的谷物由于其独特的营养成分和显著的抗逆性,在未来全球粮食安全和可持续农业方面具有明显未开发的潜力。多组学在认识未被充分研究的谷物的遗传基础和调控其独特性状的分子机制方面具有很大的前景;然而,对未充分研究的谷物的多组学研究仍然落后于对主要谷物的研究,阻碍了它们的遗传改良和在现代农业中的广泛应用。在此,我们讨论了未充分研究谷物的多组学研究的局限性和挑战,以及如何克服这些局限性和挑战,以提高对未充分研究谷物独特性状的利用,从而改善其自身和主要谷物。我们还提供了一个专门针对未被充分研究的谷物的数据库,包括来自12种未被充分研究的谷物和其中一些野生近缘种的多组学数据,以服务于社区。
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来源期刊
Nature genetics
Nature genetics 生物-遗传学
CiteScore
43.00
自引率
2.60%
发文量
241
审稿时长
3 months
期刊介绍: Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human and plant traits and on other model organisms. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation. Integrative genetic topics comprise, but are not limited to: -Genes in the pathology of human disease -Molecular analysis of simple and complex genetic traits -Cancer genetics -Agricultural genomics -Developmental genetics -Regulatory variation in gene expression -Strategies and technologies for extracting function from genomic data -Pharmacological genomics -Genome evolution
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