Cardiovascular risks in men with prostate cancer: a pragmatic, clinician-oriented review of risk stratification and management strategies.

IF 5.1 2区 医学 Q1 ONCOLOGY
Aditya Bhave, Harikrishnan Hyma Kunhiraman, Tarek Nahle, Ritu Reddy, Omar Makram, Priyanshu Nain, Viraj Shah, Umang Swami, Sagar A Patel, Ashanda Esdaille, Martha Terris, Avirup Guha
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引用次数: 0

Abstract

Background/objectives: Recent advances in prostate cancer management have improved overall survival and quality of life for those afflicted. However, these patients continue to suffer from a high burden of cardiovascular disease through a variety of mechanisms, including both the cancer itself as well as prostate cancer-specific treatments.

Subjects/methods: Cardiovascular disease is now the leading cause of death in this population, and current data suggests that many patients remain sub-optimally controlled from a risk factor standpoint. There is a lack of consensus and standardized guidelines on cardiovascular risk stratification and specific management strategies in the urology, medical oncology, radiation oncology, and primary care settings.

Results/conclusions: We review available literature and provide a cardiovascular risk stratification schema for prostate cancer patients that clinicians in each of these settings can utilize. We also highlight a shared decision-making model, consistent risk restratification, and social determinants of health as care priorities to optimize cardiovascular health for this at-risk population.

前列腺癌患者的心血管风险:一项实用的、临床导向的风险分层和管理策略综述。
背景/目的:前列腺癌治疗的最新进展提高了患者的总体生存率和生活质量。然而,这些患者通过各种机制继续遭受心血管疾病的高负担,包括癌症本身以及前列腺癌的特异性治疗。对象/方法:心血管疾病现在是这一人群的主要死亡原因,目前的数据表明,从危险因素的角度来看,许多患者仍未得到最佳控制。在泌尿外科、内科肿瘤学、放射肿瘤学和初级保健机构中,缺乏关于心血管风险分层和具体管理策略的共识和标准化指南。结果/结论:我们回顾了现有的文献,并提供了前列腺癌患者心血管风险分层方案,临床医生在这些情况下都可以使用。我们还强调将共同的决策模型、一致的风险重新定义和健康的社会决定因素作为护理重点,以优化这一高危人群的心血管健康。
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来源期刊
Prostate Cancer and Prostatic Diseases
Prostate Cancer and Prostatic Diseases 医学-泌尿学与肾脏学
CiteScore
10.00
自引率
6.20%
发文量
142
审稿时长
6-12 weeks
期刊介绍: Prostate Cancer and Prostatic Diseases covers all aspects of prostatic diseases, in particular prostate cancer, the subject of intensive basic and clinical research world-wide. The journal also reports on exciting new developments being made in diagnosis, surgery, radiotherapy, drug discovery and medical management. Prostate Cancer and Prostatic Diseases is of interest to surgeons, oncologists and clinicians treating patients and to those involved in research into diseases of the prostate. The journal covers the three main areas - prostate cancer, male LUTS and prostatitis. Prostate Cancer and Prostatic Diseases publishes original research articles, reviews, topical comment and critical appraisals of scientific meetings and the latest books. The journal also contains a calendar of forthcoming scientific meetings. The Editors and a distinguished Editorial Board ensure that submitted articles receive fast and efficient attention and are refereed to the highest possible scientific standard. A fast track system is available for topical articles of particular significance.
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