{"title":"Cannabis-based products for medicinal use in dogs and cats: a systematic review.","authors":"N Moreno-López, C Moreno-López, P Amariles","doi":"10.1111/jsap.13913","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Cannabis-based products for medicinal use, also referred to as cannabinoid-containing products, particularly those containing cannabidiol as the primary active constituent, have shown to be a possible alternative in treating various health conditions in companion animals. Thus, this systematic review aims to synthesise and analyse the available data on the efficacy/effectiveness and safety of cannabis-based products for medicinal use in dogs and cats to assist in clinical decision-making.</p><p><strong>Materials and methods: </strong>A systematic review was conducted across PubMed, LILACS, Scopus, and Google Scholar from February 2014 to February 2024. The search strategy included both MeSH terms and free-text keywords related to medical cannabis, including Medical Marijuana, Cannabis and Cannabaceae, combined with terms referring to domestic cats and dogs. Additionally, title/abstract keywords, including Cannab (as a truncated term), were used to retrieve literature on cannabinoids and their therapeutic applications.</p><p><strong>Results: </strong>Twenty-two articles were identified examining cannabidiol-based formulations for osteoarthritis, epilepsy, atopic dermatitis, postsurgical pain, and behavioural issues. Cannabis-based products for medicinal use with cannabidiol as the primary active constituent demonstrated improvements in pain, behaviour, and seizures, with no serious adverse events. However, research on their use in cats is limited to two studies.</p><p><strong>Clinical significance: </strong>While promising, the long-term efficacy/effectiveness, optimal dosages, and safety of cannabis-based products for medicinal use remain unclear. Further studies are needed to confirm their therapeutic potential and ensure safe veterinary use.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Small Animal Practice","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1111/jsap.13913","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: Cannabis-based products for medicinal use, also referred to as cannabinoid-containing products, particularly those containing cannabidiol as the primary active constituent, have shown to be a possible alternative in treating various health conditions in companion animals. Thus, this systematic review aims to synthesise and analyse the available data on the efficacy/effectiveness and safety of cannabis-based products for medicinal use in dogs and cats to assist in clinical decision-making.
Materials and methods: A systematic review was conducted across PubMed, LILACS, Scopus, and Google Scholar from February 2014 to February 2024. The search strategy included both MeSH terms and free-text keywords related to medical cannabis, including Medical Marijuana, Cannabis and Cannabaceae, combined with terms referring to domestic cats and dogs. Additionally, title/abstract keywords, including Cannab (as a truncated term), were used to retrieve literature on cannabinoids and their therapeutic applications.
Results: Twenty-two articles were identified examining cannabidiol-based formulations for osteoarthritis, epilepsy, atopic dermatitis, postsurgical pain, and behavioural issues. Cannabis-based products for medicinal use with cannabidiol as the primary active constituent demonstrated improvements in pain, behaviour, and seizures, with no serious adverse events. However, research on their use in cats is limited to two studies.
Clinical significance: While promising, the long-term efficacy/effectiveness, optimal dosages, and safety of cannabis-based products for medicinal use remain unclear. Further studies are needed to confirm their therapeutic potential and ensure safe veterinary use.
期刊介绍：
Journal of Small Animal Practice (JSAP) is a monthly peer-reviewed publication integrating clinical research papers and case reports from international sources, covering all aspects of medicine and surgery relating to dogs, cats and other small animals. These papers facilitate the dissemination and implementation of new ideas and techniques relating to clinical veterinary practice, with the ultimate aim of promoting best practice. JSAP publishes high quality original articles, as well as other scientific and educational information. New developments are placed in perspective, encompassing new concepts and peer commentary. The target audience is veterinarians primarily engaged in the practise of small animal medicine and surgery.
In addition to original articles, JSAP will publish invited editorials (relating to a manuscript in the same issue or a topic of current interest), review articles, which provide in-depth discussion of important clinical issues, and other scientific and educational information from around the world.
The final decision on publication of a manuscript rests with the Editorial Board and ultimately with the Editor. All papers, regardless of type, represent the opinion of the authors and not necessarily that of the Editor, the Association or the Publisher.
The Journal of Small Animal Practice is published on behalf of the British Small Animal Veterinary Association and is also the official scientific journal of the World Small Animal Veterinary Association
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