Four new alkaloids from Dactylicapnos grandifoliolata.

IF 1.3 3区医学 Q3 CHEMISTRY, APPLIED

Journal of Asian Natural Products Research Pub Date : 2025-07-14 DOI:10.1080/10286020.2025.2527884

Xin-Yu Liu, Jing Wu, Feng Wei, Mei-Fen Bao, Hui-Yuan Gao, Xiang-Hai Cai

引用次数: 0

Abstract

The first phytochemical investigation on D. grandifoliolata yielded twenty-four alkaloids, including four new ones, N-butylacetamide magnococline (1), fumariflorine methyl ester (6), (R)-corydalisol-2β-N-oxide (9), and (R)-coryximine-2α-N-oxide (10). Among them, compound 1 was an N-butylacetamide-substituted benzylisoquinoline alkaloid. Compounds 9 and 10 were N-oxides of benzylisoquinoline alkaloids. The structures of the new alkaloids were determined through comprehensive spectroscopic analysis and ECD calculations.

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大叶菖蒲中4个新生物碱。

首次植物化学研究共获得24种生物碱，包括4种新生物碱，分别为n -丁基乙酰胺茂葛碱(1)、富马马氟碱甲酯(6)、(R)-延胡索-2β- n -氧化物(9)和(R)-延胡索-2α- n -氧化物（10）。其中，化合物1为n -丁乙胺取代苄基异喹啉生物碱。化合物9和10为苯基异喹啉类生物碱的n -氧化物。通过综合光谱分析和ECD计算确定了新生物碱的结构。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Asian Natural Products Research 医学-药学

CiteScore

3.20

自引率

5.90%

发文量

审稿时长

2.3 months

期刊介绍： The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.