Multi-modal Cognitive Stimulation Program Improves Cognition and Quality of Life in Thai Older Adults with Mild Cognitive Impairment: A Randomized Controlled Trial.

IF 2.2 4区医学 Q3 CLINICAL NEUROLOGY

Dementia and Geriatric Cognitive Disorders Pub Date : 2025-07-14 DOI:10.1159/000547310

Phenphichcha Chuchuen, Chavit Tunvirachaisakul, Phot Dhammapeera

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引用次数: 0

Abstract

Introduction: Mild cognitive impairment (MCI) is a growing global health concern that increases dementia risk in older adults, including those in Thailand. Using an eight-session Multi-modal Cognitive Stimulation Program (MCSP) is an effective non-pharmacological intervention for slowing cognitive decline and improving cognition and quality of life (QOL).

Method: This randomized controlled trial examined the effects of an eight-session MCSP on cognition and QOL in Thai older adults with MCI. Sixty-six participants were randomized into intervention (n=32) and control (n=34) groups. Cognitive assessments included the MMSE, CERAD, Color Trails Test, and Digit Span, alongside the QOL-AD. Principal component analysis was used to aggregate cognitive assessment scores. Demographic data were analyzed using chi-square and t-tests, and Analysis of Covariance (ANCOVA) was employed for cognition and QOL outcomes.

Results: After the intervention, the MCSP group exhibited significantly higher cognitive and QOL scores than the control group. ANCOVA demonstrated that group, sex, age, education, and baseline scores significantly predicted changes in cognition and QOL outcomes. The intervention group showed significant improvements in overall cognition (F(1, 58) = 4.75, p = .033, ηp² = .076) and QOL (F(1, 58) = 6.05, p = .017, ηp² = .094).

Conclusion: An eight-session MCSP significantly improves cognition and QOL in Thai older adults with MCI, as assessed by a comprehensive cognitive battery and the QOL-AD, compared to a control group.

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多模态认知刺激计划改善泰国轻度认知障碍老年人的认知和生活质量：一项随机对照试验。

轻度认知障碍（MCI）是一个日益严重的全球健康问题，它增加了老年人（包括泰国老年人）患痴呆症的风险。使用8次多模态认知刺激计划（MCSP）是一种有效的非药物干预，可减缓认知衰退，改善认知和生活质量（QOL）。方法：本随机对照试验研究了8期MCSP对泰国老年轻度认知障碍患者认知和生活质量的影响。66名参与者随机分为干预组（n=32）和对照组（n=34）。认知评估包括MMSE、CERAD、颜色轨迹测试和数字广度，以及QOL-AD。主成分分析用于统计认知评估得分。人口统计学资料采用卡方检验和t检验，认知和生活质量指标采用协方差分析（ANCOVA）。结果：干预后，MCSP组的认知和生活质量评分显著高于对照组。ANCOVA表明，组、性别、年龄、教育程度和基线评分显著预测认知和生活质量结果的变化。干预组整体认知能力（F(1,58) = 4.75, p = 0.033, ηp²= 0.076）和生活质量（F(1,58) = 6.05, p = 0.017, ηp²= 0.094）均有显著改善。结论：通过综合认知电池和QOL- ad评估，与对照组相比，8期MCSP显著改善了泰国老年MCI患者的认知和生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dementia and Geriatric Cognitive Disorders 医学-精神病学

CiteScore

4.70

自引率

0.00%

发文量

审稿时长

2 months

期刊介绍： As a unique forum devoted exclusively to the study of cognitive dysfunction, ''Dementia and Geriatric Cognitive Disorders'' concentrates on Alzheimer’s and Parkinson’s disease, Huntington’s chorea and other neurodegenerative diseases. The journal draws from diverse related research disciplines such as psychogeriatrics, neuropsychology, clinical neurology, morphology, physiology, genetic molecular biology, pathology, biochemistry, immunology, pharmacology and pharmaceutics. Strong emphasis is placed on the publication of research findings from animal studies which are complemented by clinical and therapeutic experience to give an overall appreciation of the field.