{"title":"Advances in Polymer-Based Nanoparticles for Biomedical and Industrial Applications.","authors":"Fahad Y Sabei","doi":"10.2174/0113892010386798250708153155","DOIUrl":null,"url":null,"abstract":"<p><p>Polymeric nanoparticles (PNPs) are considered to be a revolutionary method for drug delivery and offer significantly more advantages than conventional drug delivery systems. This review synthesizes recent research on biodegradable polymers in drug delivery, emphasizing their properties, modifications, toxicity, and applications in drug absorption. It consolidates key insights from 193 research papers to offer a comprehensive overview of the field, addressing existing research gaps and highlighting various applications. Polymers can be classified based on their structure, source, and biodegradability, which are crucial for assessing their environmental impact and suitability for various applications. Polymers are categorized into two main groups based on biodegradability: biodegradable and non-biodegradable. The primary aim of this review is to elucidate the diverse applications of natural and synthetic biodegradable polymeric nanoparticles, which include cancer treatment, diabetes management, pulmonary drug delivery, and the treatment of ocular infections, all of which are thoroughly explored in this review. Additionally, the role of polymer-based hydrogels is explored as a promising solution in drug delivery. These hydrogels address issues such as poor stability and enhance treatment efficacy by ensuring the sustained release of drugs.</p>","PeriodicalId":10881,"journal":{"name":"Current pharmaceutical biotechnology","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current pharmaceutical biotechnology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2174/0113892010386798250708153155","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Polymeric nanoparticles (PNPs) are considered to be a revolutionary method for drug delivery and offer significantly more advantages than conventional drug delivery systems. This review synthesizes recent research on biodegradable polymers in drug delivery, emphasizing their properties, modifications, toxicity, and applications in drug absorption. It consolidates key insights from 193 research papers to offer a comprehensive overview of the field, addressing existing research gaps and highlighting various applications. Polymers can be classified based on their structure, source, and biodegradability, which are crucial for assessing their environmental impact and suitability for various applications. Polymers are categorized into two main groups based on biodegradability: biodegradable and non-biodegradable. The primary aim of this review is to elucidate the diverse applications of natural and synthetic biodegradable polymeric nanoparticles, which include cancer treatment, diabetes management, pulmonary drug delivery, and the treatment of ocular infections, all of which are thoroughly explored in this review. Additionally, the role of polymer-based hydrogels is explored as a promising solution in drug delivery. These hydrogels address issues such as poor stability and enhance treatment efficacy by ensuring the sustained release of drugs.
期刊介绍：
Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal includes timely in-depth reviews, original research articles and letters written by leaders in the field, covering a range of current topics in scientific areas of Pharmaceutical Biotechnology. Invited and unsolicited review articles are welcome. The journal encourages contributions describing research at the interface of drug discovery and pharmacological applications, involving in vitro investigations and pre-clinical or clinical studies. Scientific areas within the scope of the journal include pharmaceutical chemistry, biochemistry and genetics, molecular and cellular biology, and polymer and materials sciences as they relate to pharmaceutical science and biotechnology. In addition, the journal also considers comprehensive studies and research advances pertaining food chemistry with pharmaceutical implication. Areas of interest include:
DNA/protein engineering and processing
Synthetic biotechnology
Omics (genomics, proteomics, metabolomics and systems biology)
Therapeutic biotechnology (gene therapy, peptide inhibitors, enzymes)
Drug delivery and targeting
Nanobiotechnology
Molecular pharmaceutics and molecular pharmacology
Analytical biotechnology (biosensing, advanced technology for detection of bioanalytes)
Pharmacokinetics and pharmacodynamics
Applied Microbiology
Bioinformatics (computational biopharmaceutics and modeling)
Environmental biotechnology
Regenerative medicine (stem cells, tissue engineering and biomaterials)
Translational immunology (cell therapies, antibody engineering, xenotransplantation)
Industrial bioprocesses for drug production and development
Biosafety
Biotech ethics
Special Issues devoted to crucial topics, providing the latest comprehensive information on cutting-edge areas of research and technological advances, are welcome.
Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.
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