Factors Influencing Quality of Life After Intensive Care: A Systematic Review and Meta-Analysis.

IF 6 1区 医学 Q1 CRITICAL CARE MEDICINE
Critical Care Medicine Pub Date : 2025-09-01 Epub Date: 2025-07-15 DOI:10.1097/CCM.0000000000006770
Weilin Jiang, Qiqi Ni, Chuchu Zhang, Yuheng Dong, Jia Yi, Ran Yan, Zhenzhen Huang, Li Wang, Weijing Sui, Xiaoyan Gong, Yiyu Zhuang
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引用次数: 0

Abstract

Objectives: The factors influencing quality of life (QOL) after intensive care are diverse and complex, and the QOL levels remain unclear. This systematic review and meta-analysis aimed to identify the factors influencing QOL and QOL levels in post-ICU patients.

Data sources: We searched eight databases: PubMed, Embase, EBSCOhost, Cochrane Library, Web of Science, China National Knowledge Infrastructure, WeiPu, and WanFang, from inception to October 15, 2024.

Study selection: We included observational studies that examined factors influencing QOL in post-ICU patients.

Data extraction: Two independent reviewers extracted and recorded the data.

Data synthesis: A total of 65 studies, encompassing 17,298 post-ICU patients, met the inclusion criteria. The key pre-ICU factors are advanced age (per 1-yr increase) (β: -0.045 [95% CI, -0.057 to -0.033]) and female gender (odds ratio: 1.104 (95% CI, 1.035-1.177]). The key intra-ICU factors are length of ICU stay (per 1-d increase) (β: -0.012 [95% CI, -0.019 to -0.005]), length of mechanical ventilation (per 1-d increase) (β: -0.005 [95% CI, -0.009 to -0.001]), and length of hospital stay (per 1-d increase) (β: -0.107 [95% CI, -0.161 to -0.054]). The pooled overall QOL score was 58.835 (95% CI, 52.935-64.735), the pooled physical component summary (PCS) score was 49.517 (95% CI, 45.781-53.253), the pooled mental component summary (MCS) score was 53.509 (95% CI, 50.301-56.718), and the pooled overall QOL index was 0.750 (95% CI, 0.713-0.787).

Conclusions: Most pre-ICU and intra-ICU factors demonstrated strong associations with post-ICU QOL. The QOL in post-ICU patients remains at a moderate level, with the PCS score indicating greater impairment than the MCS score. Further research is highly recommended to explore effective intervention strategies to improve QOL in post-ICU patients, particularly concerning their physical well-being.

影响重症监护后生活质量的因素:系统回顾和荟萃分析。
目的:重症监护后影响患者生活质量的因素多样而复杂,其生活质量水平尚不明确。本系统综述和荟萃分析旨在确定影响icu后患者生活质量和生活质量水平的因素。数据来源:检索了PubMed、Embase、EBSCOhost、Cochrane Library、Web of Science、中国知识基础设施、微普、万方等8个数据库,检索时间自成立至2024年10月15日。研究选择:我们纳入了观察性研究,研究了影响icu后患者生活质量的因素。数据提取:两名独立评审员提取并记录数据。数据综合:共有65项研究,包括17,298名icu后患者,符合纳入标准。icu前的关键因素是高龄(每增加1年)(β值:-0.045 [95% CI, -0.057 ~ -0.033])和女性(优势比:1.104 (95% CI, 1.035 ~ 1.177])。ICU内的关键因素是ICU住院时间(每增加1 d) (β: -0.012 [95% CI, -0.019至-0.005])、机械通气时间(每增加1 d) (β: -0.005 [95% CI, -0.009至-0.001])和住院时间(每增加1 d) (β: -0.107 [95% CI, -0.161至-0.054])。合并总体生活质量评分为58.835 (95% CI, 52.935 ~ 64.735),合并身体成分总结评分为49.517 (95% CI, 45.781 ~ 53.253),合并精神成分总结评分为53.509 (95% CI, 50.301 ~ 56.718),合并总体生活质量指数为0.750 (95% CI, 0.713 ~ 0.787)。结论:大多数icu前和icu内因素与icu后生活质量密切相关。icu后患者的生活质量维持在中等水平,PCS评分比MCS评分显示更大的损害。我们强烈建议进一步研究有效的干预策略,以改善icu后患者的生活质量,特别是关注他们的身体健康。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Critical Care Medicine
Critical Care Medicine 医学-危重病医学
CiteScore
16.30
自引率
5.70%
发文量
728
审稿时长
2 months
期刊介绍: Critical Care Medicine is the premier peer-reviewed, scientific publication in critical care medicine. Directed to those specialists who treat patients in the ICU and CCU, including chest physicians, surgeons, pediatricians, pharmacists/pharmacologists, anesthesiologists, critical care nurses, and other healthcare professionals, Critical Care Medicine covers all aspects of acute and emergency care for the critically ill or injured patient. Each issue presents critical care practitioners with clinical breakthroughs that lead to better patient care, the latest news on promising research, and advances in equipment and techniques.
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