Comprehensive and continuous nursing strategies in perioperative management of upper urinary tract stones treated with holmium laser lithotripsy.

IF 1.9 3区医学 Q3 UROLOGY & NEPHROLOGY

BMC Urology Pub Date : 2025-07-14 DOI:10.1186/s12894-025-01850-3

Ying Qiu, Weiying Huang, Li Ouyang

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引用次数: 0

Abstract

Objective: This research aims to analyze the effects of total, continuous nursing interventions as a perioperative care system for patients undergoing percutaneous nephrolithotripsy (PCNL) with upper urinary tract stones on postoperative: inflammatory response, oxidative stress, and stress hormones.

Methods: In the study, 150 patients with upper urinary tract stones (renal and proximal upper urinary tract stones) underwent PCNL from January 2023 to December 2024. The patients were then randomly assigned into two groups; the control group (75 patients) received conventional nursing care interventions, and the study group (75 patients) received comprehensive and continuous nursing interventions. Postoperative levels of inflammatory markers (CRP, IL-10), oxidative stress indicators (MDA, SOD), and stress hormones (COR, ACTH, NE) were compared between the two groups. Additionally, the incidence of postoperative complications and length of hospital stay were recorded.

Results: The study group exhibited significantly lower levels of postoperative inflammatory markers compared to the control group (p < 0.05). Improvements in oxidative stress indicators were notable, with a significant reduction in MDA levels and a marked increase in SOD levels (p < 0.05). Furthermore, stress hormone levels (COR, ACTH, NE) in the study group were significantly lower than those in the control group (p < 0.05). The incidence of postoperative complications in the study group (5.56%) was significantly lower than that in the control group (20.83%), with a reduced length of hospital stay and increased patient satisfaction (p < 0.05).

Conclusion: The collaborative and continuous nursing strategy almost completely avoids postoperative inflammatory responses, reduces oxidative stress, and regulates the secretion of stress-related hormones, greatly improving recovery outcomes for upper urinary tract stone patients undergoing PCNL.

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钬激光碎石治疗上尿路结石围手术期的综合持续护理策略。

目的：本研究旨在分析全面、持续护理干预作为经皮肾镜碎石术（PCNL）合并上尿路结石患者围手术期护理体系对术后炎症反应、氧化应激及应激激素的影响。方法：在研究中，从2023年1月到2024年12月，150例上尿路结石（肾结石和近端上尿路结石）患者接受了PCNL。然后将患者随机分为两组；对照组（75例）采用常规护理干预，研究组（75例）采用综合持续护理干预。比较两组术后炎症标志物（CRP、IL-10）、氧化应激指标（MDA、SOD）及应激激素（COR、ACTH、NE）水平。此外，还记录了术后并发症的发生率和住院时间。结果：研究组术后炎症标志物水平明显低于对照组(p)。结论：协同持续护理策略几乎完全避免了术后炎症反应，降低了氧化应激，调节了应激相关激素的分泌，大大改善了PCNL上尿路结石患者的恢复效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Urology UROLOGY & NEPHROLOGY-

CiteScore

3.20

自引率

0.00%

发文量

177

审稿时长

>12 weeks

期刊介绍： BMC Urology is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of urological disorders, as well as related molecular genetics, pathophysiology, and epidemiology. The journal considers manuscripts in the following broad subject-specific sections of urology: Endourology and technology Epidemiology and health outcomes Pediatric urology Pre-clinical and basic research Reconstructive urology Sexual function and fertility Urological imaging Urological oncology Voiding dysfunction Case reports.