Kazim Kerim Moncal, Laeya Abdoli Najmi, Rakhi Gupta, Malavika Ramarao, Joshua W. Knowles, Chong Y. Park, Naside Gozde Durmus
{"title":"Label-Free Detection of Lipid Accumulation in Cells Using Magnetic Levitation (Adv. Biology 7/2025)","authors":"Kazim Kerim Moncal, Laeya Abdoli Najmi, Rakhi Gupta, Malavika Ramarao, Joshua W. Knowles, Chong Y. Park, Naside Gozde Durmus","doi":"10.1002/adbi.70026","DOIUrl":null,"url":null,"abstract":"<p><b>Label-Free Detection of Lipid Accumulation via Magnetic Levitation</b></p><p>Magnetic levitation can be used for label-free profiling and characterization of lipid accumulation within cells, by separating cells based on their biophysical profiles. As pre-adipocytes differentiate, lipid accumulation occurs, leading to lower cell density and higher levitation heights. Four distinct layers can be seen within the magnetic levitation device: lipid vesicles (at top), mature adipocytes, adipocytes, and pre-adipocytes. More details can be found in article number 2200142 by Naside Gozde Durmus and co-workers.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":7234,"journal":{"name":"Advanced biology","volume":"9 7","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adbi.70026","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced biology","FirstCategoryId":"99","ListUrlMain":"https://advanced.onlinelibrary.wiley.com/doi/10.1002/adbi.70026","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0
Abstract
Label-Free Detection of Lipid Accumulation via Magnetic Levitation
Magnetic levitation can be used for label-free profiling and characterization of lipid accumulation within cells, by separating cells based on their biophysical profiles. As pre-adipocytes differentiate, lipid accumulation occurs, leading to lower cell density and higher levitation heights. Four distinct layers can be seen within the magnetic levitation device: lipid vesicles (at top), mature adipocytes, adipocytes, and pre-adipocytes. More details can be found in article number 2200142 by Naside Gozde Durmus and co-workers.