Label-Free Detection of Lipid Accumulation in Cells Using Magnetic Levitation (Adv. Biology 7/2025)

IF 2.6 3区 生物学 Q3 MATERIALS SCIENCE, BIOMATERIALS
Kazim Kerim Moncal, Laeya Abdoli Najmi, Rakhi Gupta, Malavika Ramarao, Joshua W. Knowles, Chong Y. Park, Naside Gozde Durmus
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引用次数: 0

Abstract

Label-Free Detection of Lipid Accumulation via Magnetic Levitation

Magnetic levitation can be used for label-free profiling and characterization of lipid accumulation within cells, by separating cells based on their biophysical profiles. As pre-adipocytes differentiate, lipid accumulation occurs, leading to lower cell density and higher levitation heights. Four distinct layers can be seen within the magnetic levitation device: lipid vesicles (at top), mature adipocytes, adipocytes, and pre-adipocytes. More details can be found in article number 2200142 by Naside Gozde Durmus and co-workers.

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利用磁悬浮无标记检测细胞内脂质积累(ad . Biology 7/2025)
通过磁性悬浮无标记检测脂质积累磁性悬浮可用于无标记分析和表征细胞内脂质积累,方法是根据细胞的生物物理特征分离细胞。随着前脂肪细胞分化,脂质积累发生,导致细胞密度降低和悬浮高度升高。在磁悬浮装置内可以看到四个不同的层:脂质囊泡(顶部)、成熟脂肪细胞、脂肪细胞和前脂肪细胞。更多细节可以在Naside Gozde Durmus及其同事的2200142号文章中找到。
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来源期刊
Advanced biology
Advanced biology Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)
CiteScore
6.60
自引率
0.00%
发文量
130
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