Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal-Phenolic Networks (Adv. Healthcare Mater. 18/2025)
Chenyu Wang, Ailifeire Fulati, Kenta Kimura, Xianglan Li, Joseph J. Richardson, Mitsuru Naito, Kanjiro Miyata, Takanori Ichiki, Hirotaka Ejima
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引用次数: 0
Abstract
Small Extracellular Vesicles
In article 2405188, Hirotaka Ejima and co-workers introduce a selectively disassemblable surface modification approach for small extracellular vesicles (sEVs) utilizing metal-phenolic networks that post-modified with polyethylene glycol. Such nanocoating significantly enhances the storage stability of sEVs and allows selectively triggered disassembly of encapsulated shells for the retrieval of intact and functional sEVs, thereby facilitating efficient storage, transport and subsequent promising biomedical applications.
期刊介绍:
Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.