Laryngeal squamous cell carcinoma in a 4-year-Old child: A rare case report

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology Pub Date : 2025-07-09 DOI:10.1016/j.ijporl.2025.112482

Mukhtar Baryare Matan , Abdullahi Ahmed Tahlil , Nafisa Ahmed Mohamed , Abdifatah Mohamed Tahlil , Mohamed Abdirahman Omar , Omar Mohamed Hassan , Ismail Gedi İbrahim , Hussein Osman Abdulle , Abdullahi Ali Moallim Hussein , Christian Ayele , Kassim Hagi Hossain , Yahye A. Mohamud Shoole

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引用次数: 0

Abstract

Laryngeal Squamous Cell Carcinoma (LSCC) is an extremely rare malignancy cancer in children, accounting for less than 1 % of head and neck cancers in those under 18. This case report discusses a 4-year-old boy with a three-year history of worsening respiratory distress and stridor, who was ultimately diagnosed with superficially invasive squamous cell carcinoma of the larynx. The child showed significant symptoms that led to further assessment. Indirect laryngoscopy revealed a whitish lesion on the left vocal cord and posterior commissure. Microlaryngoscopy under general anesthesia allowed complete removal of the lesion, initially thought to be juvenile papillomatosis. However, histopathology confirmed LSCC, showing acanthotic stratified squamous epithelium with marked pleomorphism and lamina propria invasion. This case emphasizes the importance of early detection and treatment of pediatric laryngeal cancer, despite its rarity and the risk of misdiagnosis. It adds to the limited literature on this condition and underscores the need for clinicians to remain vigilant when evaluating respiratory symptoms in children.

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4岁儿童喉部鳞状细胞癌一例罕见报告

喉鳞状细胞癌（喉鳞状细胞癌）是一种极为罕见的儿童恶性肿瘤，占18岁以下儿童头颈部癌症的不到1%。这个病例报告讨论了一个4岁的男孩，他有三年的呼吸窘迫和喘鸣病史，最终被诊断为喉部表面浸润性鳞状细胞癌。该儿童表现出明显的症状，导致进一步的评估。间接喉镜检查发现左侧声带及后连合处有一白色病变。全身麻醉下的喉镜检查完全切除病变，最初认为是幼年乳头状瘤。然而，组织病理学证实LSCC，显示棘皮层状鳞状上皮具有明显的多形性和固有层浸润。这个病例强调了早期发现和治疗小儿喉癌的重要性，尽管它的罕见和误诊的风险。它增加了关于这种情况的有限文献，并强调了临床医生在评估儿童呼吸道症状时保持警惕的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International journal of pediatric otorhinolaryngology 医学-耳鼻喉科学

CiteScore

3.20

自引率

6.70%

发文量

276

审稿时长

62 days

期刊介绍： The purpose of the International Journal of Pediatric Otorhinolaryngology is to concentrate and disseminate information concerning prevention, cure and care of otorhinolaryngological disorders in infants and children due to developmental, degenerative, infectious, neoplastic, traumatic, social, psychiatric and economic causes. The Journal provides a medium for clinical and basic contributions in all of the areas of pediatric otorhinolaryngology. This includes medical and surgical otology, bronchoesophagology, laryngology, rhinology, diseases of the head and neck, and disorders of communication, including voice, speech and language disorders.