Process mining to identify average time patterns of changes in FAMACHA© scores in ewes and guide monitoring intervals

IF 2.2 2区农林科学 Q2 PARASITOLOGY

Veterinary parasitology Pub Date : 2025-07-08 DOI:10.1016/j.vetpar.2025.110543

Matheus Borges de Carvalho , Diógenes Adriano Duarte Santana , Laize Guedes Carmo , Saulo Henrique Weber , Eric R. Morgan , Deborah Ribeiro Carvalho , Cristina Santos Sotomaior

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引用次数: 0

Abstract

Frequent blanket treatment with anthelmintics (AH) leads to selection of resistant parasites. Targeted Selective Treatment (TST) methodologies were developed to support more discriminating decisions on AH treatment of individual animals. Criteria like FAMACHA© scores (F-scores, a measure of anemia) detect changes in animal health to trigger treatment, but require effort and so the appropriate frequency of monitoring must be considered. Process mining can be used to define optimal intervals for TST application by analyzing flows between states over time. The aim of this study was therefore to evaluate the average time taken for changes in the F-scores of adult ewes using process mining. The study was performed by analyzing a database containing F-score evaluations from 2006 to 2022, using UpFlux© software. From 2017–2022 ewes were categorized based on their physiological state. Ewes in late gestation and lactation were classified as likely to be more susceptible to parasites, while non-pregnant and early pregnant ewes were considered as less susceptible. When considering data for the entire flock from 2017 to 2022, an average of 97 ewes were evaluated weekly, and they spent a mean of 78.5 days at F-score 1 (F1) and 25.0 days at F2. Based on F-score fluctuations, ewes progressed from F1 to F2 in an average of 59.1 days and from F2 to F3 in an average of 26.3 days. Ewes in the more susceptible physiological states maintained F1 and F2 scores for an average of 34.1 and 20.0 days, respectively. Their transition from score F2 (non-anemic) to F3 (anemic) occurred in an average of 19.7 days. Ewes in less susceptible physiological states maintained F1 for 68.2 days and F2 for 24.5 days, while F2 changed to F3 after an average of 29.6 days. Based on the results, evaluations for TST should be conducted more frequently (every 15 days) in ewes during late pregnancy and lactation, while a 30-day interval is sufficient for other physiological states. This method could be used to evaluate optimal intervals for F-scoring in other settings, to guide efficient animal health monitoring and intervention strategies.

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过程挖掘识别母羊FAMACHA©得分变化的平均时间模式，并指导监测间隔

频繁使用驱虫药进行地毯式治疗导致产生耐药寄生虫。开发了靶向选择性治疗（TST）方法，以支持对单个动物的AH治疗做出更具歧视性的决定。FAMACHA©评分（f -评分，贫血的一种衡量标准）等标准可以检测到动物健康状况的变化，从而引发治疗，但需要付出努力，因此必须考虑适当的监测频率。流程挖掘可以通过分析状态之间随时间的流动来定义TST应用程序的最佳间隔。因此，本研究的目的是利用过程挖掘来评估成年母羊f分数变化的平均时间。本研究使用UpFlux©软件，通过分析包含2006年至2022年F-score评估的数据库进行。2017-2022年，根据母羊的生理状态对母羊进行分类。妊娠后期和哺乳期的母羊被归类为可能更容易感染寄生虫，而未怀孕和怀孕早期的母羊被认为不太容易感染寄生虫。考虑2017 - 2022年全羊群的数据，平均每周评估97只母羊，平均f评分为1 （F1）的78.5天，F2的25.0天。根据f -评分的波动，母羊从F1到F2平均需要59.1天，从F2到F3平均需要26.3天。生理状态较敏感的母羊F1和F2评分平均维持时间分别为34.1天和20.0天。他们从F2分（非贫血）到F3分（贫血）的转变平均发生在19.7天。生理状态较弱的母羊F1维持68.2 d， F2维持24.5 d， F2平均29.6 d后变为F3。综上所述，母羊在妊娠晚期和哺乳期应更频繁地（每15天）进行TST的评估，而其他生理状态的评估间隔30天就足够了。该方法可用于评估其他环境中f评分的最佳间隔，以指导有效的动物健康监测和干预策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary parasitology 农林科学-寄生虫学

CiteScore

5.30

自引率

7.70%

发文量

126

审稿时长

36 days

期刊介绍： The journal Veterinary Parasitology has an open access mirror journal,Veterinary Parasitology: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. This journal is concerned with those aspects of helminthology, protozoology and entomology which are of interest to animal health investigators, veterinary practitioners and others with a special interest in parasitology. Papers of the highest quality dealing with all aspects of disease prevention, pathology, treatment, epidemiology, and control of parasites in all domesticated animals, fall within the scope of the journal. Papers of geographically limited (local) interest which are not of interest to an international audience will not be accepted. Authors who submit papers based on local data will need to indicate why their paper is relevant to a broader readership. Parasitological studies on laboratory animals fall within the scope of the journal only if they provide a reasonably close model of a disease of domestic animals. Additionally the journal will consider papers relating to wildlife species where they may act as disease reservoirs to domestic animals, or as a zoonotic reservoir. Case studies considered to be unique or of specific interest to the journal, will also be considered on occasions at the Editors'' discretion. Papers dealing exclusively with the taxonomy of parasites do not fall within the scope of the journal.