Ray tracing-guided LASIK for high myopia and astigmatism: Initial clinical outcomes

IF 2.6 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-07-11 DOI:10.1016/j.pdpdt.2025.104715

Lei Luo , Yimeng Fan , Xindi Wang , Linjuan Yang , Shimin Tan , Yu Zhang , Yan Cai , Jingni Yu , Zhao Liu , Shengjian Mi , Qianyan Kang

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引用次数: 0

Abstract

Objective

To evaluate visual acuity, refractive outcomes and ocular higher order aberrations (HOAs) following ray tracing-guided laser-assisted in situ keratomileusis (LASIK) for high myopia and astigmatism.

Methods

This retrospective study enrolled 77 eyes in 42 patients with high myopia and astigmatism undergoing ray tracing-guided LASIK. InnvoEyes Sightmap was used for ocular wavefront aberrometry, tomography and biometry assessment. Visual acuity, refractive error and ocular HOAs were evaluated preoperatively and 3 months postoperatively.

Results

Preoperative manifest refraction spherical equivalent (MRSE) was -7.52 ± 0.86 D (sphere:6.87 ± 1.02 D; cylinder:1.29 ± 0.82 D). At 3 months, 100 % of eyes achieved uncorrected distance visual acuity (UDVA) ≥ 20/20 with no loss of CDVA. Refractive outcomes showed MRSE within ± 0.50 D in 97 % of eyes and astigmatism within ± 0.25 D in 83 % of eyes. The correction index demonstrated high accuracy (arithmetic: 1.09; geometric: 1.07) with minimal difference vector (0.04 D@99°). While ocular total HOA increased from 0.209 ± 0.080 µm to 0.330 ± 0.108 (p < 0.001), spherical aberration maintained comparable values (0.034 ± 0.067 µm vs 0.038 ± 0.086 µm, p = 0.700).

Conclusions

Ray tracing-guided LASIK demonstrated favorable safety, efficacy and predictability for high myopia and astigmatism in this study. Notably, spherical aberration maintained its values after the procedure, suggesting the potential of ray tracing-guided LASIK to optimize visual acuity and refractive outcomes in the correction of high myopia.

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射线追踪引导LASIK治疗高度近视和散光：初步临床结果：射线追踪引导LASIK治疗高度近视和散光。

目的：评价射线追踪引导激光辅助原位角膜磨圆术（LASIK）治疗高度近视和散光后的视力、屈光效果和高阶像差（HOAs）。方法：回顾性研究42例高度近视散光患者，77眼，行射线追踪引导LASIK手术。使用innoveyes视图进行眼波前像差测量、断层扫描和生物测量评估。术前和术后3个月分别评估视力、屈光不正和眼hoa。结果：术前明显折射球等效（MRSE）为-7.52±0.86 D(球等效：-6.87±1.02 D；气缸：-1.29±0.82 D)。3个月时，100%的眼睛达到非矫正距离视力(UDVA)≥20/20，无CDVA损失。屈光结果显示97%的眼睛MRSE在±0.50 D内，83%的眼睛散光在±0.25 D内。校正指标精度高(算术：1.09；几何：1.07)，最小差分向量（0.04 D@99°）。眼总HOA从0.209±0.080µm增加到0.330±0.108µm (p < 0.001)，球差保持相当的值（0.034±0.067µm vs 0.038±0.086µm, p = 0.700）。结论：在本研究中，射线追踪引导LASIK治疗高度近视和散光具有良好的安全性、有效性和可预测性。值得注意的是，手术后球差保持在其值，这表明射线追踪引导LASIK在矫正高度近视中具有优化视力和屈光结果的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.