Echoes of the larynx: harnessing acoustic analysis as a key tool for monitoring laryngeal health in inhalational therapy patients.

IF 0.8 4区医学 Q3 OTORHINOLARYNGOLOGY

Journal of Laryngology and Otology Pub Date : 2025-07-14 DOI:10.1017/S0022215125102752

Sharad Ashish, Nirmal Coumare V, Pajanivel R, Padmanabhan Karthikeyan

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Abstract

Objectives: This study evaluated laryngeal changes and voice quality in patients with obstructive lung disease treated with combination inhalational agents.

Methods: A prospective observational study at a tertiary care hospital in southern India included 112 newly diagnosed obstructive lung disease patients. Initial assessments involved history-taking, clinical examination, direct laryngoscopy and voice analysis using PRAAT® software. Parameters such as mean pitch, jitter, shimmer, harmonic-to-noise ratio and maximum phonation time were measured, with follow-ups at 3, 6 and 12 months.

Results: Patients had a mean age of 43.05 years. Progressive laryngeal changes, including oedema (5.3 per cent) and hyperaemia (7.1 per cent), were noted by 12 months. Significant increases in shimmer and jitter, along with decreases in harmonic-to-noise ratio and maximum phonation time, indicated deteriorating voice quality (p < 0.001).

Conclusion: Long-term inhalational corticosteroid use in obstructive lung disease patients leads to progressive laryngeal changes and voice deterioration, emphasising the need for vocal function monitoring and preventive strategies.

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喉的回声：利用声学分析作为监测吸入治疗患者喉部健康的关键工具。

目的：本研究评价联合吸入性药物治疗阻塞性肺疾病患者的喉部变化和语音质量。方法：在印度南部的一家三级医院进行前瞻性观察研究，包括112名新诊断的阻塞性肺病患者。初步评估包括病史记录、临床检查、直接喉镜检查和使用PRAAT®软件进行声音分析。测量平均音高、抖动、闪烁、谐波噪声比和最大发声时间等参数，并于3、6和12个月随访。结果：患者平均年龄43.05岁。12个月时发现进行性喉部改变，包括水肿（5.3%）和充血（7.1%）。闪烁和抖动的显著增加，以及谐波噪声比和最大发声时间的减少，表明语音质量恶化（p < 0.001）。结论：阻塞性肺疾病患者长期吸入性皮质类固醇可导致进行性喉部改变和声音恶化，强调需要对声带功能进行监测和预防策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Laryngology and Otology 医学-耳鼻喉科学

CiteScore

3.20

自引率

11.80%

发文量

593

审稿时长

3-6 weeks

期刊介绍： The Journal of Laryngology & Otology (JLO) is a leading, monthly journal containing original scientific articles and clinical records in otology, rhinology, laryngology and related specialties. Founded in 1887, JLO is absorbing reading for ENT specialists and trainees. The journal has an international outlook with contributions from around the world, relevant to all specialists in this area regardless of the country in which they practise. JLO contains main articles (original, review and historical), case reports and short reports as well as radiology, pathology or oncology in focus, a selection of abstracts, book reviews, letters to the editor, general notes and calendar, operative surgery techniques, and occasional supplements. It is fully illustrated and has become a definitive reference source in this fast-moving subject area. Published monthly an annual subscription is excellent value for money. Included in the subscription is access to the JLO interactive web site with searchable abstract database of the journal archive back to 1887.