The Long-Term Impact of ADHD on Children and Adolescents' Health-Related Quality of Life: Results From a Longitudinal Population-Based Australian Study.

IF 2.7 3区 医学 Q2 PSYCHIATRY
Ha Nguyet Dao Le, Courtney Keily, David Coghill, Lisa Gold
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Abstract

Background: ADHD is the most common neurodevelopmental disorder. While much is known about the functional and academic impacts of ADHD, impacts on long-term health-related quality of life (HRQoL) are less well-documented.

Aims: To explore, in children aged 4 to 17 years, associations between clinical ADHD symptoms and (1) children's HRQoL; (2) whether internalizing or externalizing problems attenuate this association; and (3) factors contributing to this association.

Methods: Data were drawn from the Longitudinal Study of Australian Children at child ages 4 to 17 years (N = 4,194). Clinical ADHD symptoms (e.g., score >8) were measured using the hyperactivity scale from the Strengths and Difficulties Questionnaire (SDQ). Internalizing or externalizing problems were classified as children with scores ≥5 on the Emotional Problems and scores ≥4 on the Conduct Problems scale on the SDQ, respectively. Children's HRQoL was measured using the Pediatric Quality of Life Inventory (PedsQL). Linear mixed models were used, adjusting for child and family factors.

Results: Compared to those with no ADHD symptoms, children with ADHD symptoms had significantly lower HRQoL across all domains from 4 to 17 years (mean difference = 7.65, 95% CI [6.09, 9.19]). Internalizing and externalizing problems slightly attenuated the association between ADHD symptoms and children's HRQoL (mean difference = 4.91, 95% CI [3.40, 6.43]). Being a female or having autism or other medical conditions, or taking ADHD/ADD medication or caregiver having mental health problems was associated with poorer HRQoL while having two or more siblings was associated with better HRQoL.

Conclusion: ADHD clinical symptoms are associated with poorer children's HRQoL from 4 to 17 years. Given that co-occurring medical conditions and poor caregiver mental health are associated with poorer child HRQoL, ADHD treatment needs to identify and address co-occurring conditions and parental mental health.

ADHD对儿童和青少年健康相关生活质量的长期影响:来自澳大利亚一项纵向人群研究的结果
背景:ADHD是最常见的神经发育障碍。虽然人们对多动症的功能和学业影响了解很多,但对长期健康相关生活质量(HRQoL)的影响却没有很好的记录。目的:探讨4 ~ 17岁儿童ADHD临床症状与儿童HRQoL的关系;(2)内部化或外部化问题是否会减弱这种关联;(3)促成这种关联的因素。方法:数据来自澳大利亚4 - 17岁儿童纵向研究(N = 4,194)。临床ADHD症状(例如,> - 8分)采用优势与困难问卷(SDQ)中的多动量表进行测量。内化或外化问题分别被分类为SDQ中情绪问题得分≥5分和行为问题得分≥4分的儿童。使用儿科生活质量量表(PedsQL)测量儿童的HRQoL。采用线性混合模型,对儿童和家庭因素进行调整。结果:与没有ADHD症状的儿童相比,有ADHD症状的儿童在4至17岁的所有领域的HRQoL均显著降低(平均差异= 7.65,95% CI[6.09, 9.19])。内化和外化问题轻微减弱ADHD症状与儿童HRQoL之间的关联(平均差异= 4.91,95% CI[3.40, 6.43])。女性或患有自闭症或其他疾病,或服用ADHD/ADD药物或照顾者有精神健康问题的人的HRQoL较差,而有两个或更多兄弟姐妹的人的HRQoL较好。结论:ADHD临床症状与4 ~ 17岁儿童HRQoL较差相关。鉴于同时发生的医疗状况和照顾者心理健康状况不佳与儿童较差的HRQoL相关,ADHD治疗需要识别和解决同时发生的状况和父母的心理健康问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.60
自引率
6.70%
发文量
71
审稿时长
6-12 weeks
期刊介绍: Journal of Attention Disorders (JAD) focuses on basic and applied science concerning attention and related functions in children, adolescents, and adults. JAD publishes articles on diagnosis, comorbidity, neuropsychological functioning, psychopharmacology, and psychosocial issues. The journal also addresses practice, policy, and theory, as well as review articles, commentaries, in-depth analyses, empirical research articles, and case presentations or program evaluations.
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