Association of HRQOL with Symptom Patterns in an Online Cohort of Patients with Interstitial Cystitis/Bladder Pain Syndrome.

IF 2.1 3区医学 Q2 UROLOGY & NEPHROLOGY

Urology Pub Date : 2025-07-10 DOI:10.1016/j.urology.2025.06.054

Anthony Galvez, Paige Kuhlmann, Margot Barker, Andrew Chen, Victoria Scott, Karyn Eilber, Jennifer Anger

{"title":"Association of HRQOL with Symptom Patterns in an Online Cohort of Patients with Interstitial Cystitis/Bladder Pain Syndrome.","authors":"Anthony Galvez, Paige Kuhlmann, Margot Barker, Andrew Chen, Victoria Scott, Karyn Eilber, Jennifer Anger","doi":"10.1016/j.urology.2025.06.054","DOIUrl":null,"url":null,"abstract":"Objectives: To explore the differences in symptom patterns and management between individuals with IC/BPS who have high vs low self-reported health related quality of life (HRQOL).Methods: An anonymous 40-question online survey assessed IC/BPS patients' symptoms, triggers, management strategies, and comorbidities. Recruitment was through the Interstitial Cystitis Association's Facebook page. HRQOL was rated on a 0-10 Likert scale, grouping respondents into low-impact (0-3), intermediate (4-6), and high-impact (7-10). Univariate analysis included chi-square, Fisher's exact test, and t-tests.Results: Among 451 respondents, 53 (12%) reported low disease impact, while 279 (62%) had high impact. The high-impact group was more frequently triggered by mental health issues (50% vs 32%, p=0.016) and exercise (14% vs 4%, p=0.040), while the low-impact group was more often triggered by allergies (6% vs 1%, p=0.054) and coffee (11% vs 3%, 0.005). High-impact individuals had higher rates of comorbidities including pelvic floor dysfunction (39% vs 19%, 0.005), irritable bowel syndrome (36% vs 21%, p=0.029), overactive bladder (30% vs 17%, p=0.051), and/or vulvodynia (23% vs 9%, p=0.026).Conclusions: IC/BPS encompasses a spectrum of disease manifestations. While demographics remain relatively uniform in this IC/BPS population, symptom patterns, comorbidities, and therapeutic choices are correlated with impact on quality of life.","PeriodicalId":23415,"journal":{"name":"Urology","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.urology.2025.06.054","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives: To explore the differences in symptom patterns and management between individuals with IC/BPS who have high vs low self-reported health related quality of life (HRQOL).

Methods: An anonymous 40-question online survey assessed IC/BPS patients' symptoms, triggers, management strategies, and comorbidities. Recruitment was through the Interstitial Cystitis Association's Facebook page. HRQOL was rated on a 0-10 Likert scale, grouping respondents into low-impact (0-3), intermediate (4-6), and high-impact (7-10). Univariate analysis included chi-square, Fisher's exact test, and t-tests.

Results: Among 451 respondents, 53 (12%) reported low disease impact, while 279 (62%) had high impact. The high-impact group was more frequently triggered by mental health issues (50% vs 32%, p=0.016) and exercise (14% vs 4%, p=0.040), while the low-impact group was more often triggered by allergies (6% vs 1%, p=0.054) and coffee (11% vs 3%, 0.005). High-impact individuals had higher rates of comorbidities including pelvic floor dysfunction (39% vs 19%, 0.005), irritable bowel syndrome (36% vs 21%, p=0.029), overactive bladder (30% vs 17%, p=0.051), and/or vulvodynia (23% vs 9%, p=0.026).

Conclusions: IC/BPS encompasses a spectrum of disease manifestations. While demographics remain relatively uniform in this IC/BPS population, symptom patterns, comorbidities, and therapeutic choices are correlated with impact on quality of life.

查看原文本刊更多论文

间质性膀胱炎/膀胱疼痛综合征在线队列患者HRQOL与症状模式的关联

目的：探讨自我报告健康相关生活质量（HRQOL）高与低的IC/BPS患者在症状模式和管理方面的差异。方法：一项包含40个问题的匿名在线调查评估了IC/BPS患者的症状、触发因素、管理策略和合并症。招募是通过间质性膀胱炎协会的Facebook页面进行的。HRQOL以0-10的李克特量表进行评分，将受访者分为低影响（0-3），中级（4-6）和高影响（7-10）。单变量分析包括卡方检验、费雪精确检验和t检验。结果：在451名受访者中，53名（12%）报告疾病影响低，279名（62%）报告疾病影响高。高影响组更常被心理健康问题（50%对32%，p=0.016）和运动（14%对4%，p=0.040）触发，而低影响组更常被过敏（6%对1%，p=0.054）和咖啡（11%对3%，0.005）触发。高影响个体的共病发生率较高，包括盆底功能障碍（39%对19%，0.005）、肠易激综合征（36%对21%，p=0.029）、膀胱过度活动（30%对17%，p=0.051）和/或外阴痛（23%对9%，p=0.026）。结论：IC/BPS包括一系列疾病表现。虽然IC/BPS人群的人口统计数据保持相对一致，但症状模式、合并症和治疗选择与生活质量的影响相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Urology 医学-泌尿学与肾脏学

CiteScore

3.30

自引率

9.50%

发文量

716

审稿时长

59 days

期刊介绍： Urology is a monthly, peer–reviewed journal primarily for urologists, residents, interns, nephrologists, and other specialists interested in urology The mission of Urology®, the "Gold Journal," is to provide practical, timely, and relevant clinical and basic science information to physicians and researchers practicing the art of urology worldwide. Urology® publishes original articles relating to adult and pediatric clinical urology as well as to clinical and basic science research. Topics in Urology® include pediatrics, surgical oncology, radiology, pathology, erectile dysfunction, infertility, incontinence, transplantation, endourology, andrology, female urology, reconstructive surgery, and medical oncology, as well as relevant basic science issues. Special features include rapid communication of important timely issues, surgeon''s workshops, interesting case reports, surgical techniques, clinical and basic science review articles, guest editorials, letters to the editor, book reviews, and historical articles in urology.